摘要
目的:探讨达英-35联合二甲双胍治疗多囊卵巢综合征的临床疗效。方法:将64例多囊卵巢综合征患者随机分为观察组和对照组,各32例,观察组采用达英-35联合二甲双胍治疗,对照组采用达英-35治疗,比较两组疗效及不良反应。结果:治疗后两组患者的黄体生成激素和睾酮较治疗前下降明显,观察组与对照组比较差异有统计学意义(P<0.05),观察组排卵率为71.88%,自然妊娠率为56.25%,对照组分别为53.13%和18.75%,两组比较有差异有统计学意义(P<0.05),服药过程中均未见明显不良反应。结论:达英-35联合二甲双胍治疗多囊卵巢综合征可促使异常升高的促性腺激素及雄激素恢复正常,改善促排卵效果,提高妊娠率,不良反应少,值得临床推广。
Objective：To investigate the clinical effect of Diane-35 combined with Metformin in the treatment of polycystic ovary syndrome.Methods：64 patients with polycystic ovary syndrome were randomly divided into treatment group and control group,with 32 cases in each group,the observation group was given Diane-35 combined with Metformin,and the control group was given Diane-35,the efficacy and adverse reactions between the two groups were compared.Results：After treatment,the luteinizing hormone and testosterone decreased significantly than before treatment,and compared with control group after treatment,the difference was statistically significant（P〈0.05）.In the observation group,the ovulation rate was 71.88%,the natural pregnancy rate was 56.25%,which of control group were 53.13% and 18.75% respectively,the differences between the two groups were statistically significant（P〈0.05）.There were no significant adverse reactions in the process of taking medicine of the two groups.Conclusion：Diane-35 combined with Metformin in treating polycystic ovarian syndrome can contribute to abnormal increasing of gonadotropin and testosterone return to normal,improve the effectiveness of ovulation induction and the pregnancy rate,and reduce adverse reactions,which is worthy of promotion.
出处
《中国医药导报》
CAS
2011年第36期80-81,共2页
China Medical Herald
