多囊卵巢综合征的现状与研究进展被引量：25

Current status and progress in study on polycystic ovary syndrome

导出

摘要多囊卵巢综合征是以雄激素过多及长期无排卵为特征,育龄妇女常见的一种极为复杂的内分泌及糖代谢异常所致的病理状态。其基本病理生理不确切,目前认为主要与胰岛素抵抗、高雄激素血症、促性腺激素动力学改变相关。至于诊断标准有NIH标准和ESHRE/ASRM标准。典型的临床表现为闭经、不孕、多毛和肥胖,治疗上主张对症性治疗。 Polycystic ovary syndrome is a common pathologic condition of women in reproductive age which is characterized by chronic anovulation and clinical or biochemical features of hyperandrogenism, including complicated endocrine disorders and metabolic disturbances. The fundamental pathophysiologic defect is not determined.Many reseachers considered that it is associated with insulin resistance, hyperandrogenism, and altered gonadotropin dynamics. The criteria of PCOS diagnosis are controversial, including NIH and ESHRE/ASRM criteria. Typical clinical manifestations of PCOS include amenorrhea, infertility, hirsutism and obesity. The treatment strategies are all symptomatic.[

作者季银芬石一复

机构地区浙江大学医学院附属妇产科医院

出处《国外医学（妇幼保健分册）》 2005年第3期175-178,共4页 Foreign Medical Sciences (Section of Maternal and Child Health)

关键词多囊卵巢综合征胰岛素抵抗诊断治疗 polycystic ovary syndrome insulin resistance diagnosis treatment

分类号 R711.75 [医药卫生—妇产科学]

引文网络
相关文献

参考文献9

1Diamanti K E, Kouli C R, Bergiele A T, et al. A survey of the polycystic ovary syndrome in the Greek island of Lesbos:hormonal and metabolic profile [J]. J Clin Endocrinol Metab,1999,84 : 4006-4011.
2Ovalle F,Azziz R.Insulin resistance,polysystic ovary syndrome, and type 2 diabetes mellitus[J]. Fertil steril,2002,77(6):1095-1105.
3Robert J, Norman, Ruijin W U, et al. Polycystic ovary syndrome[J]. MJA,2004,180(3):132-137.
4Saleh A M, Khalil H S. Review of nonsurgical and surgical treatment and the role of insulin-sensitizing agents in the management of infertile women with polycystic ovary syndrome[J]. Acta Obstet Gynecol Scand,2004,83(7):614-621.
5Nestle J E. Should patients with polycystic ovarian syndrome be treated with metformin? :an enthusiastic endorsement[J]. Hum Reprod,2002,17(8):1950-1953.
6Pirwany I R,Yates R W S,Cameron I T,et al.Effects of the insulin sensitizing drug metformin on ovarian function,follicular growth and ovulation rate in obese women with oligomenorrhea[J]. Hum Repord, 1999,14:2963-2968.
7Iuorno M J, Nestler J E. Insulin-lowering drugs in polycystic ovary syndrome[J]. Obstet Gynecol Clin North Am, 2001,28 :153-164.
8Costello M F, Eden I A. A systematic review of the reproductive systeme effects of metformin in patients with polycystic ovary syndrome[J]. Fertil Steril,2003,79(1):1-13.
9Ramzy A M, AI I H, Aboulfoutouh I, et al. Ultrosonography guided ovarian stroma hydrocoagulation for ovarian stimulation in polycystic ovary syndrome [J].Acta Obstet Gynecol Scand,2001,80(11):1046-1050.