摘要
目的探讨急性主动脉夹层（AAD）患者血清B型钠尿肽（BNP）水平与病情程度及预后的关系。方法测定42例AAD患者血清BNP浓度，根据血清BNP增高的程度将42例患者分为A、B2组。A组23例，BNP峰值≥500ng／L；B组19例，BNP〈500ng／L。分析血清BNP浓度与病情程度及预后的关系。结果42例AAD患者BNP浓度均增高，A组中发生夹层继续分离及住院期间病死率分别为47．83％（11／23）、26．09％（6／23），明显高于B组[15．79％（3／19）、0]，差异均有统计学意义（P值分别为0．048、0．024）。结论AAD患者血清中的BNP浓度与病情程度及预后有关。
Objective To investigate the relationship among the levels of B-type natriuretic peptide （BNP） and the extent, prognosis of acute aortic dissection （AAD）. Methods The serum levels of BNP were measured in 42 AAD cases. According to the increasing level of BNP,the patients were divided into two groups： group A （ BNP ≥ 500 ng/L, n = 23 ） and group B（ BNP 〈 500 ng/L, n = 19 ）. The extent of the disease and cardiovascular events were compared between the two groups. Results All the patients have elevated levels of BNP. The incidence of lasting aortic dissection （47. 83% vs. 15.79%, P = 0. 048 ） and mortality （ 26.09% vs. 0, P = 0. 024） were higher in group A compared with those of group B. Conclusion The lasting and higher levels of BNP predict the increasing risk of bad prognosis in acute aortic dissection.
出处
《中国综合临床》
2011年第12期1257-1258,共2页
Clinical Medicine of China
关键词
主动脉夹层
B型钠尿肽
预后
Aorta dissection
B-type natriuretic peptide
Prognosis
