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TP、NP两种方案结合同步放疗治疗中晚期非小细胞肺癌疗效对比研究 被引量:1

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摘要 目的:比较TP、NP方案结合同步放疗治疗中晚期非小细胞肺癌的临床疗效以及化疗及放疗的不良反应。方法:选择中晚期非小细胞肺癌(NSCLC)患者64例,随机法分为两组,一组为紫杉醇+顺铂组(TP组32例),一组为盖诺+顺铂组(NP组32例)。两组患者分别行2周期TP或NP方案化疗后,行常规放射治疗。放疗采用6MV-X线,照射原发灶和区域淋巴结,DT=60Gy,分割剂量2Gy/(次·日),5次/周。结果:TP组治疗有效率59.3%(19/32),NP组治疗有效率53.1%(17/32),两组比较无显著性差异(P>0.05);TP组及NP组不良反应相似,但NP组骨髓抑制较TP组轻,均可耐受。结论:TP方案及NP方案同步放化疗治疗中晚期非小细胞肺癌临床效果较好;同步放化疗联合治疗未增加治疗毒性。
作者 徐鸿洁
出处 《中国社区医师(医学专业)》 2011年第35期96-96,共1页
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