摘要
目的:观察支气管动脉灌注化疗联合局部放疗治疗中晚期肺癌临床疗效;方法:选取2005年6月～2008年5月就诊于我科的中晚期肺癌患者72例,年龄42～76岁,平均(54.3±4.5)岁。采用介入化疗加放疗治疗,并与2000年2月～2004年7月我院采用单纯化疗的58例中晚期肺癌患者临床资料进行对比。结果:介入化疗加放疗组有效率为48.6%,疾病控制率为86.1%。单纯放射治疗组有效率为32.8%,疾病控制率70.7%。两组患者RR、DCR均有显著差异,P<0.05。远期疗效,介入化疗加放疗组3月生存率86.1%,1年生存率70.8%,3年生存率52.8%;对照组3月生存率74.1%,1年生存率50.0%,3年生存率25.7%。两组患者3月、1年、3年生存率均有显著差异,P<0.05。结论:支气管动脉灌注化疗联合放疗效果显著,创伤小,值得临床推广。
purpose ： observing clinical effect of mid and late lung cancer using combination of bronchial arterial infusion chemo- therapy and partial radiotherapy; method： selecting 72 cases of mid and late lung cancer patients who have been treated in our department from June, 2005 - May, 2008 with the age ranging between 42 - 76 and 54. 3 ±4. 5 on average. By using interfering chemotherapy and radiotherapy, and comparing clinical data of 58 cases of mid and late lung cancer patients who are treated with pure chemotherapy in our hospital from Feb, 2000 -July, 2004. Result： the effective rate of the group using interfering chemotherapy and radiotherapy is 48.6% with disease control rate being 86. 1%, while those for the group with pure radiotherapy are 32.8% and 70. 7%. RR and DCR of the two groups of patients are of remarkable difference with P 〈 0. 05. Long -term curative effect： sur- vival rate for the group with interfering chemotherapy and radiotherapy for three months is 86. 1% and 70. 8% for one year, 52.8% for three years; and corresponding data for the matched group are 74. 1%, 50. 0% and 25.7% respectively. The survival rate for the two groups of patients for three months, one year and three years are of remarkable differences with P 〈 0. 05. Conclusion： the effect of combination of bronchial arterial infusion chemotherapy and partial radiotherapy is very striking with small trauma, so it is worth being spread clinically.
出处
《中国民族民间医药》
2011年第24期33-34,共2页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
支气管动脉灌注
化疗
放疗
中晚期肺癌
bronchial arterial infusion
chemotherapy
radiotherapy
mid and late lung cancer
