摘要
目的旨在通过超敏肌钙蛋白Ⅰ(TropI)和传统肌钙蛋白I(cTnI)检测方法的比较,探讨其在心肌炎诊断中的临床意义。方法收集2009～2010年30例门诊和住院患者血液标本,检测血清肌钙蛋白值,比较两种方法的精密性、相关性、阳性率以及离散率。结果 TropI的变异系数(CV)(6.948%)明显低于cTnI(18.190%),两种方法检测肌钙蛋白的均值与相应的质控靶值比较差异无统计学意义(P>0.05)。对这两种方法检测的结果进行回归分析显示相关性良好(r2=0.981 2);两种方法检测患者血清cTnI组平均CV值(7.655%)高于TropI组平均CV值(2.116%),差异有统计学意义(P<0.01)。结论两种方法在检测血清肌钙蛋白的作用上基本一致,但是Tropi在重复性方面优于传统的cTnI检测,可能更有利于心肌炎的诊断。
Objective To explore the clinical significance in the diagnosis of myocarditis by comparing TropI with previous cTnI. Methods 30 cases of outpatient and inpatient blood specimens from 2009 to 2010 in our hospital were collected. Then the value of serum troponin I blood samples were detected for each blood samples. The precision,relevance,positive rate and outlier rate were compared. Results The CV （6. 948%） of TropI was significantly lower than the CV（18.19%） of cTnI. There was no statistically significant differences between the mean troponin blood samples and quality controi target value （P〉0.05）. The two methods of regression analysis showed high correlation（r2 =0. 981 2）. The average CV value of serum cTnI （7. 655%） and TropI average CV value （2. 116%） were relatively high. The results showed no significant differences （P〈0.01）. Conclusion The two methods are basically the same on the role of testing serum troponin. However, Hypersensitivity troponin is better than the traditional eTnI detection method on the repeatability, therefore Hypersensitivity troponin may be more conducive to the diagnosis of myocarditis.
出处
《检验医学与临床》
CAS
2011年第24期2964-2965,共2页
Laboratory Medicine and Clinic
