摘要
目的：探讨深低温冷冻同种异体肌腱替代自体肌腱的可行性及移植后异体肌腱的生物力学性能的动态变化。方法：采用兔跟腱缺损修复模型，以经深低温冷冻的同种异体跟腱为实验组，自体跟腱移植为对照组，分别在术前及术后２、４、８ 周时对实验组及对照组跟腱进行生物力学测试。结果：同种异体跟腱与自体跟腱在移植前和移植后２、４、８ 周时其生物力学测试的各项指标均无显著性差异。另外，同种异体跟腱在移植后其力学性能（除衰竭应变外）均比移植前明显降低。随时间推进有上升的趋势，但８ 周时仍明显低于移植前。结论：深低温冷冻同种异体肌腱可替代自体肌腱应用于移植修复肌腱缺损。同时，由于移植后肌腱力学性能明显下降，需给予适当保护。
Objective:To study the reliability of deep frozen allogeneic tendons as a substitute of autograft and the change of biomechanics after transplantation.Methods:The model of defect repair of the Achilles tendons of rabbits was used.Deep frozen allogeneic tendons were taken as treatment group and autogenous ones as controls.The biomechanical tests were performed on both of them before transplantation and in 2,4 and 8 weeks after transplantation.Results:There were no differences in mechanical strength between allograft and autograft both before and after transplantation.Whats more,the mechanical strength of allograft (except failure strain) was reduced significantly after transplantation.However,it had a rising trend with time passing although fairly low in 8 weeks compared with the normal.Conclusion:Deep frozen allograft can substitute for autograft in repairing the tendon defect,and owing to the weakness after transplantion,it need appropriate protection to prevent failure by excessive strain in early stage.
出处
《滨州医学院学报》
1999年第6期526-529,共4页
Journal of Binzhou Medical University
