摘要
实验采用激光测量装置，测定了在不同温度及反应物浓度下，普鲁卡因青霉素溶液微粒结晶过程的反应及成核时间，通过最优化方法模拟得到普鲁卡因青霉素溶液微粒结晶过程的反应动力学；通过采用ＭＳＭＰＲ结晶器以及聚结－破裂粒数衡算模型，得到了普鲁卡因青霉素溶液微粒结晶的结晶动力学。
Reaction and nucleation time were measured under the different conditions of temperature and concentration by using laser detection technique. After optimization calculation and parameter estimation, a reactive kinetics of crystallization of Procaine benzylpenicillin, and crystallization kinetics including agglomeration and breakage was also obtained by MSMPR crystallizer.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1999年第6期408-409,414,共3页
Chinese Journal of Antibiotics
关键词
普鲁卡因青霉素
溶液
微粒结晶
动力学
Procaine benzylpenicillin
Solution micro crytalline
Reactive kinetics
Crystal lizatiom kinetics
