摘要
目的探讨妊娠合并血小板减少症的病因、临床特征和诊治。方法选取蚌埠第三人民医院2004年1月-2011年6月间就诊的38例妊娠合并血小板减少症患者进行回顾性分析。结果妊娠合并血小板减少症的病因为妊娠相关性血小板减少(PAT)24例,免疫性血小板减少症(ITP)7例,再生障碍性贫血2例,营养性巨幼细胞性贫血2例,急性白血病1例,系统性红斑狼疮2例。治疗方法是给予糖皮质激素或丙种球蛋白或输注血小板等,其中23例行剖宫产,有1例出现产后出血,所有患者均未出现新生儿颅内出血及新生儿死亡。结论妊娠期血小板减少原因较多并且多发生于妊娠中晚期,应积极治疗合并症和并发症,预防出血倾向及加强胎儿监护。对于血小板<50×109/L或有严重出血倾向的患者可予以糖皮质激素和(或)人血丙种球蛋白治疗,产前适当提高血小板水平,可以减少并发症的出现。
Objective To study the pathogeny,clinical characteristic,diagnosis and treatment of thrombocytopenia in pregnancy.Methods The clinical data of 38 pregnancies with thrombocytopenia from Jan.2004 to Jun.2011 in our hospital was analyzed retrospectively.Results In all 38 cases,24 were with pregnancy-associated thrombocytopenia（PAT）,7 with immune thrombocytopenia,2 with aplastic anemia（AA）,2 with nutritional megaloblastic anemia,1 with acute leukemia（AL）,2 with systemic lupus erythematosus（SLE）.Glucocorticoid,immunoglobulin or platelet transfusion was selectively administered.The cesarean section was performed in 23 cases,and 1 case was with posrpartum hemorrhage.There was no intracranial hemorrhage of the newborn and perinatal mortality.Conclusion A number of causes may result in thrombocytopenia in pregnancy that mostly occurred in the middle-late pregnancy.More attentions should be paid on the treatment of complication to prevent the haemorrhage and carefully neonatal intensive care.For the patients with platelet less than 50×109/L or serious bleeding tendency,glucocorticoid or immunoglobulin should be given to increase their amount of platelet before the delivery and decrease the rate of the complications.
出处
《中华全科医学》
2011年第12期1886-1886,1925,共2页
Chinese Journal of General Practice
关键词
妊娠
血小板减少
病因
Pregnancy
Thrombocytopenia
Causes
