摘要
目的：阿立哌唑与经典药物舒必利对精神分裂症患者生活质量的影响。方法：筛选80例精神分裂症患者，随机分为两组，研究组使用阿立哌唑，对照组使用舒必利，采用阳性症状和阴性症状评定量表（PANSS）、副反应量表（TESS）评价治疗8周后生活质量的改善情况。结果：治疗2周后两纽患者的PANSS评分较治疗前显著降低，8月末与治疗前存在显著差异，但阿立哌唑椎体外系反应小，副作用较少。结论：阿立哌唑与舒必利比较，疗效与舒必利相当，对患者的社交能力、日常生活质量和认知功能损伤较小，值得临床推广应用。
Objective： To investigate the sulpifide and aripiprazole in patients with schizophrenia quality of life. Methods：Use positive symptoms and negative symptoms rating scale （PANSS）, side effects scale （TESS） evaluation of hospital 80 cases ilbr schizophrenia in patients with sulpiride or aripiprazole treatment quality of life improvements. Results： Treatment after 2 weeks the two groups were PANSS score significandy lower than that before treatment, 8 weeks before treatment were significandy different. Conclusion： Afipiprazole and allpifide compared to former patients of the negative .symptoms and positive symptoms have a better effect on the patient＇s social skills, daily quality of life and les cognitive impairment, is worthy of clinical appfication.
