摘要
目的观察壳聚糖止血敷料联合充气止血绷带应用于桡动脉穿刺点压迫止血的临床效果。方法将经桡动脉入路实施冠状动脉介入检查和治疗的310例患者随机分为对照组和试验组,每组155例。对照组采用桡动脉充气止血绷带常规方法压迫止血,试验组使用壳聚糖止血辅料联合桡动脉充气止血绷带压迫止血。所有患者试验前至少接受阿司匹林100 mg/d和(或)氯吡格雷75 mg/d治疗3 d。比较两组患者桡动脉压迫时间和出血并发症发生率。结果试验组的穿刺点压迫时间为(184.8±23.3)min,显著短于对照组的(364.8±23.6)min(P<0.01)。试验组的出血并发症发生率为1.9%(3/155),显著低于对照组的7.7%(12/155,P=0.012)。结论壳聚糖止血辅料联合充气止血绷带应用于经桡动脉入路实施冠状动脉介入检查和治疗后穿刺点的压迫止血,能明显缩短压迫时间,降低出血并发症发生率,效果安全可靠。
Objective To investigate the clinical outcomes of chitosan combined with a tourniquet bandage for hemostasis of radial artery puncture. Methods A total of 310 patients who had undergone transradial angiography （TRA） or transradial intervention （TRI） were randomly divided into 2 groups （n = 155）. The control group was treated with radial compression device （TR-BAND, Terumo）; the study group was treated by chitosan combined with the radial compression device. All the patients received aspirin （100 mg/d） or clopidogrel （75 mg/d） at least for 3 days. The radial compression time and complications were compared between the two groups. Results The average compression time of puncture point in the study group （[184.8±23.31 min） was significantly shorter than that in the control group （F364.8±23.61 min, P〈0.01 ）. The incidence rate of bleeding in the study group （1.9%, 3/155） was significantly lower than that in the control group （7.7%, 12/155, P = 0.012）. Conclusion Chitosan combined with a tourniquet bandage can obviously shorten the compression time and reduce the incidence of complications （bleeding and errhyis） following radial artery puncture. And the outcomes is reliable and safe. （Shanghai Med J, 2011, 34： 773-775）
出处
《上海医学》
CAS
CSCD
北大核心
2011年第10期773-775,共3页
Shanghai Medical Journal
关键词
壳聚糖
桡动脉
压迫止血
Chitosan
Radial artery
Compression haemostasis
