摘要
妊娠合并白血病发生率不高,但由于并发症严重,易导致母婴死亡,临床处理较为棘手。白血病对妊娠母体及胎儿具有显著性的损害,而妊娠状态对白血病可能并无明显影响。妊娠合并白血病的临床处理需要严格区分妊娠状态,早孕患者建议立即停止妊娠后积极治疗白血病,中晚孕患者应积极足量化疗,辅以支持疗法,争取在短期内完全缓解。影响患者预后的主要因素是及时诊断并尽早开始强力化疗以提高缓解率和可能的治愈率。
Sununary： The incidence of leukemia during pregnancy is not high, but its serious complications result easily in maternal and infant mortality, making it a difficult clinical problem. Leukemia causes significant damage to the pregnant mother and fetus while pregnancy may not significantly affect the leukemia. Clinical treatment of leukemia during pregnancy requires strict discrimination of the pregnancy state. Patients with early pregnancy should give up the fetus and receive chemotherapy; patients in late pregnancy should undergo adequate chemotherapy, combined with a supportive therapy,in order to achieve complete remission in a short term. The main prognostic factors are an early diagnosis and an early start of chemotherapy to improve the response rate and obtain a possible cure.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第12期915-917,共3页
Chinese Journal of Practical Internal Medicine
关键词
白血病
妊娠
化疗
leukemia
pregnancy
chemotherapy
