摘要
目的:探讨肺炎支原体肺炎(MPP)急性期、恢复期患儿的免疫功能变化。方法:采用流式细胞仪技术检测了35例急性期支原体肺炎患儿及其中24例恢复期患儿外周血CD3、CD4、CD8,用速率散射比浊法检测血清IgA、IgG、IgM,并与30例正常儿童进行比较。结果:MPP组急性期及恢复期较正常儿童的血清IgG及IgA水平降低(急性期P<0.01,恢复期P<0.05),CD3及CD4水平降低(均P<0.01)。结论:体液免疫和细胞免疫参与了MPP感染的发病过程,且存在免疫功能降低及紊乱。
Objective：To investigate the Immune Function changes in children with mycoplasma pneumonia（MPP） both on acute stage and onconvalescence stage.Methods：35 Cases with acute-phased MPP and the 24 recovery-phased of them and 30 healthy children served as control were involved in this study.CD3＋ CD4＋ /CD8＋ T lymphocyte in the peripheral blood were determined by flow cytometry.The levels of IgG,IgA,and IgM were measured by velocity scatter colorimetry.Results：The serum IgG and IgA levels（the acute-phased P0.01,the recovery-phased P0.05）,CD3 and CD4（mean P0.01）.Conclusions：Humoral immunity and cellular immunity involve in the episode of MPP infection,with the presence of decreasing derangement of immunological function.
出处
《航空航天医学杂志》
2011年第11期1307-1309,共3页
Journal of Aerospace medicine
关键词
肺炎支原体
肺炎
免疫球蛋白
T淋巴细胞亚群
Mycoplasm apneumoniae pneumonia
Immune globulin
T-lymphocyte subsets
