期刊文献+

对比三种制备方法对血小板活化状态的影响 被引量:1

暂未订购
导出
摘要 目的分析不同制备方法对血小板活化状态的影响。方法选择2010年12月符合无偿献血标准的献血者的血液45份,根据制备血小板方法的不同分为P组、B组、T组,三组分别采用富血小板血浆法、白膜回浆法、血细胞分离机单采法,对比三组血小板表面CD62P阳性表达率和血浆可溶性CD62P(sCD62P)的表达水平。结果 T组的CD62P阳性表达率和sCD62P表达水平明显低于B组和P组,P组的CD62P阳性表达率和sCD62P表达水平明显高于T组和B组,差异均具有统计学意义(P<0.05)。结论血细胞分离机单采法制备的血小板活化状态最低,富血小板血浆法制备的血小板活化状态最高。
作者 欧阳波
机构地区 长沙血液中心
出处 《中外医学研究》 2011年第33期43-44,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
  • 相关文献

参考文献2

二级参考文献10

  • 1马明信.临床医学概要[M].北京:人民卫生出版社,1998.196.
  • 2Perseghln P, Mascaretti L, Speranza T, et al. Platelet activation during plasma-reduced multicomponent PLT collection., a comparison between COBE Trima and Spectra LRS turbo cell separators [J]. Transfusion, 2004,44(1):125-130.
  • 3Curvers J, de Wildt-Eggen J, Heeremans J, et al. Flow cytometric measurement of CD62P (P-selectin) expression on platelets: a multicenter optimization and standardization effort [J]. Transfusion, 2008, 48 (7):1439-1446.
  • 4Gutensohn K,Geidel K,Brockman M,et al. Binding of activated platelets to WBCs in vivo after transfusion[J].Transfusion,2002,42 (10) : 1373-1380.
  • 5Kyrle PA,Hron G,Eichinger S,et al. Circulating p-selectin and the risk of recurrent venous thromboembolism[J]. Thromb Haemost, 2007,97 (6) : 880-883.
  • 6Skripchenko A,Kurtz J, Moroff G,et al. Platelet products prepared by different methods of sedimentation undergo platelet activation differently during storage [J].Transfusion, 2008,48 (7) : 1469-1477.
  • 7Barnard MR, MacGregor H, Mercier R, et al. Platelet surface p-selectin,platelet-granulocyte heterotypic aggregates,and plasma-soluble p-selectin during plateletpheresis[J]. Transfusion, 1999,39 (7) : 735-741.
  • 8Stiegler G,Eichelberger B,Leitner G,et al. Response to vWF-coated beads and soluble p-selectin to characterize apheresis platelets: a comparison of three cell separators[J]. Transfusion, 2002,42 (3) : 375-379.
  • 9Tynngrd N ,Lindahl TL, Trinks M, et al. The quality of platelet concentrates produced by COBE Spectra and Trima Aecel cell separators during storage for 7 days as assessed by in vitro methods[J]. Transfusion, 2008,48 (4):715-722.
  • 10欧阳锡林,刘景汉,石群,高大勇.优化流式细胞术测定保存血小板CD62p表达[J].中国实验血液学杂志,2002,10(5):462-465. 被引量:15

共引文献5

同被引文献7

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部