摘要
目的探讨Graves病（GD）患者甲状腺组织剪切波速度的变化及其与促甲状腺激素（TsH）的相关性。方法应用声辐射力脉冲成像技术（ARFI）中声触诊组织量化技术（VTQ），对40例Graves患者及30例正常对照者的甲状腺组织进行超声弹性量化检测，分析GD患者甲状腺组织剪切波速度的变化及其与TSH的相关性。结果GD患者甲状腺组织不同部位剪切波速度均低于正常对照组相应部位，差异有统计学意义（Pd0．05）。GD患者甲状腺组织剪切波速度在不同部位间差异无统计学意义，两两间比较差异均无统计学意义（P〉0．05），GD患者甲状腺组织平均剪切波速度与TSH呈中度正相关（r=0．707）。结论甲状腺组织剪切波速度可作为GD诊断的一项辅助指标，可间接反映TSH的水平，为GD的治疗提供一定的参考。
Objective To investigate the changes of the shear wave velocities on thyroid tissues in patients with Graves disease（GD） and its correlation with thyrotropin （TSH）. Methods Forty GD patients and 30 health adults who underwent an ultrasoun＆based acoustic radiation force impulse （ARFI） technique, the shear wave velocity of thyroid tissues was obtained using virtual touch tissue quantification （VTQ） of ARFI technique,and the changes of the shear wave velocities on thyroid tissues with GD patients and its correlation with the serum TSH level were analyzed. Results The shear wave velocities of thyroid tissues in patients with GD was lower than that of normal, thas were significant difference（ P 〈0.05）, but there were no significant differences among different locations in GD patients（ P 〉0.05）. The shear wave velocities of thyroid tissues were correlated with the serum TSH level in patients with GD, the correlation coefficient was 0. 707. Conclusions The shear wave velocity may be considered as a helpful index in diagnosing GD and indirectly reflect the serum TSH level,provide some reference for therapy of the GD.
出处
《中华超声影像学杂志》
CSCD
北大核心
2011年第11期962-964,共3页
Chinese Journal of Ultrasonography
