期刊文献+

血小板生长因子及其受体在排斥反应中的意义

暂未订购
导出
摘要 血小板生长因子最初是被认为在动脉粥样硬化中起作用,它是促使动脉内膜增厚、平滑肌细胞增生的原因之一。实验研究证实了这种假设,即血小板可粘附于血管内皮的剥落处,并释放血小板生长因子,促使平滑肌细胞增生,以致内膜增厚,使血管腔变窄。动脉粥样硬化(Atherosclerosis)与器官移植后的排斥反应性动脉血管硬化(TranplantAtherosclerosis)类似,都以平滑肌细胞增生为主,使血管腔变窄。
作者 江艺 夏穗生
出处 《南京部队医药》 1995年第2期76-78,共3页
  • 相关文献

参考文献11

  • 1Berk BC,Alexander RW,Brock TA et al.Vasocon-striction, a new activity for platelet-derived growth factor. Science . 1986
  • 2Ross R,Raines EW,Bowen-Poper DF.The biology of platelet-derived growth factor. Cell . 1986
  • 3Higgy NA,Davidoff AW,Bendiktsson H et al.Platelet-dericed growth factor recepor expression in chronic rejection of cardiac and renal grafts in the rat. Transplantation Proceedings . 1991
  • 4Hart CE,Forstrstrom JW,Kelly JD et al.Two classes of PDGF receptor recognize differnt isoform of PDGF. Science . 1988
  • 5Fellstrom B,Klareskog L,Heldin CH et al.Platelet-derived growth factor receptora in the kidney-upregulated expression in inflammation. Kidney International . 1989
  • 6Fellstrom B,Klareskog L,Larsson E et al.Tissue distribution of macrophages, class Ⅱ transplantation transplantion antigens and receptors for platelet-derived growth factor in normal and rejected human kidneys. Transplantation Proceedings . 1987
  • 7Yaarden Y,Escobedo JA,Kuang WJ et al.Structure of the receptor fmr platelet-derived growth factor helps define a family of closely related growth factor receptor. Nature . 1986
  • 8Raines EW,Dower SK,Ross R.Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science . 1989
  • 9Heldin CH,Hammacher A,Nister M et al.Structure and function aspects of platelet-derived growth factor. British Journal of Cancer . 1988
  • 10Sporn MB,Roberts AB.Peptid growth factors are muti-factorial. Nature . 1988

共引文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部