摘要
酮酸制剂能被慢性肾衰的动物和病人吸收，结合体内的氨，通过转氨酶的作用形成相应的氨基酸供机体合成蛋白质，同时降低非蛋白氛的水平。另外，某些酮酸通过多种可能机制发挥一定的药理作用。临床实验表明酮酸制剂的疗效优于相应的氨基酸，但必须强调低蛋白饮食和供给足够的热量。随着对酮酸制剂的进一步研究，将显著提高酮酸的治疗效果。
Oral ketoacids can be absorbed by animal and patients with chronic renal faifure, then combine with amino group to form corresponding essential amino acids thiough transaminase; and decrease plasma level of non-protein nitrogen. Moreover some ketoacids have certain pharmacologic effects.With low protein diet and enough calories, clinical trials showed ketoacids had some advantages over amino acids in treatmeat. Ketoacids will have better therapeutic effect with further study.
出处
《中华临床营养杂志》
CAS
1998年第4期182-185,共4页
Chinese Journal of Clinical Nutrition
