摘要
目的:应用二维斑点追踪成像技术(2D-STI)定量分析左室短轴收缩功能,评价二维斑点追踪成像技术在检出胸部放疗后对心脏早期损伤方面的应用价值。方法:46例接受胸部放疗的恶性肿瘤患者按照放疗进程分为3组:A组:放疗前(对照组);B组:放疗时间2.5～3周、照射剂量26～30Gy;C组:放疗时间5～6周、照射剂量50～60Gy。测量左心室基底段、中段短轴方向峰值径向应变(RS)及圆周应变(CS)。结果:①C组前壁、前间隔和后壁各节段的RS和CS较A组明显减低(P<0.01);C组前壁、前间隔和后壁各节段的RS和CS较B组减低(P<0.05);B组前壁、前间隔和后壁各节段的RS和CS与A组比较无显著性差异(P>0.05)。②下壁、侧壁和后间隔各节段的RS和CS在各组之间无显著性差异(P>0.05)。结论:研究表明胸部放疗达到一定时间和剂量时,被照心肌组织的RS和CS均比放疗前明显减低,说明已出现心脏局部的收缩功能受损。二维斑点追踪成像技术对评价胸部放疗后的早期心脏损伤具有重要价值。
Objective： To evaluate the vakte of speckle tracking imaging （STI） in detecting early thoracic radiotherapy-in- duced myocardial damage by using STI to quantitatively analyse the left ventricular systolic function at short-axial view. Methods： STI was performed in 46 patients with thoracic radiotherapy. The 46 patients were divided into three groups： group A： before radiation treatment （control group）; group B： radiotherapy time was 2.5-3 weeks, radiotherapy dose was 26-30Gy; group C： radiotherapy time was 5-6 weeks, radiotherapy dose was 50~60Gy. Radial strain （RS） and circumferential strain（CS） were measured in the left ventricular short-axial view at the levels of mitral annulus and papillary muscle. Results： ①RS and CS of group C in anterior wall, anterior septal and posterior wall were significantly lower than those in group A （P〈O.01）; RS and CS of group C in anterior wall, anterior septal and posterior wall were lower than those in group B （P〈0.05）; RS and CS of group B in anterior wall, anterior septal and posterior wall compared with those in group A, had no significant difference （P〉0.05）; ②RS and CS of left lateral wall, posterior septal and inferior wall in all groups had no significant difference （P〉 0.05）. Conclusions： RS and CS after the thoracic radiation treatment were significantly lower than those in the patients before radiation treatment, STI can indicate the change of heart disease in systolic function. STI is valuable to assess early thoracic radiotherapy-induced myocardial damage.
出处
《中国临床医学影像杂志》
CAS
北大核心
2011年第10期701-703,共3页
Journal of China Clinic Medical Imaging
