摘要
研究了氨水溶液中,FeCl3与盐酸多巴胺反应生成紫红色络合物,其最大吸收波长为507 nm,络合比为1:2。体系的吸光度与盐酸多巴胺的浓度在20.0～220 mg/L范围内呈良好的线性关系,线性回归方程A=0.00842+0.11844ρ(mg/L),相关系数r=0.9991,表观摩尔吸光系数ε=2.25×104 L.mol-1 cm-1,检出限为0.021 mg/L,相对标准偏差为0.71%。据此建立了测定盐酸多巴胺的新方法,能够直接用于注射液中盐酸多巴胺的测定,回收率为95.3%～100.2%。
A new method is established for the determination of dopamine hydrochloride （DPH） using ferric trichloride. This method is based on the formation of a red compound from the reaction of DPH and ferric trichloride in ammonia water solution. The maximum absorption wavelength and the value of 85o7 were 507 nm and 2. 25 × 104 L · mol^-1 · cm^-1 , respectively, when the stoichiometric ratio of the reaction was 1：2. Beer＇s law was obeyed in the range of 20. 0 - 220 mg/L for DPH. The linear regression equation was A = 0. 00842 ＋ 0. 11844p （mg/L） with a correlation coefficient of 0. 9991. The detection limit was 0. 021 rag/L, while RSD was 0. 71% （32. 0 mg/L, n = 11 ）. This method is applied to the determination of DPH in injections with recoveries of 95.3% - 100. 2%.
出处
《分析试验室》
CAS
CSCD
北大核心
2011年第11期89-91,共3页
Chinese Journal of Analysis Laboratory
基金
平顶山学院高层次人才科研启动经费项目(2008009)资助
关键词
盐酸多巴胺
分光光度法
FECL3
Dopamine hydrochloride
Spectrophotometry
Ferric trichloride
