摘要
目的应用Ⅲ类磁力矫治器建立青春期恒河猴动物模型,观察其对颅面部形态学及颅面骨缝的组织学影响,并探讨其机制。方法选用生长发育期雄性恒河猴6只,实验组45、90 d各2只,对照组45、90 d各1只。实验组配戴铸造式磁力矫治器,对照组不戴用矫治器。采用头颅侧位片测量分析其颅颌面的形态学变化。选用颅面部6条骨缝作为观察对象,应用活体荧光染色及苏木精-伊红染色观察其组织学变化。结果所有实验动物颌位均出现明显近远中移位,90 d组的变化较45 d组更为明显,对照组无明显变化。荧光染色及苏木精-伊红染色观察显示:实验组各骨缝均表现为明显的骨沉积,尤其是颧颌缝、腭横缝、翼腭缝、颧颞缝最为明显。结论Ⅲ类磁力矫治器可以引起上下颌骨以及牙齿位置的变化,并可使颅面骨缝内纤维结缔组织排列方向发生变化,导致骨缝两侧新骨的大量沉积。
Objective To investigate the influence of class Ⅲ forces in craniofacial morphology and sutural histo-logy in Rhesus monkeys.Methods Six male Rhesus monkeys in mixed dentition were employed in this study,two as 90-day experimental group,two as 45-day experimental group and the other two as control respectively.The experi-mental monkeys were casted magnetic orthopedic appliance-Ⅲ（MOA-Ⅲ）,the control monkeys received no treatment.Intraoral photographs,casts and cephalometric radiographs of each animal were obtained at the beginning and at the end of the experiment.Fluorescent and haematoxylin-eosin staining were used to observe the histological changes in craniofacial sutures.Results In experimental groups,the maxillomandibular relationship changed more significantly in 90-day experimental group than 45-day experimental animals.But changes were scarcely noted in the control.The bony depositions of the sutures were distinctly found during the experimental period,especially in zygomaticomaxillary,trans-verse palatine,pterygopalatine and zygomaticotemporal sutures.Conclusion This study indicates that this kind of mag-netic appliance could cause skeletal and dental changes of maxilla and mandible,and change the arrangement of con-nective tissues in craniofacial sutures,and lead to significant new bone deposition in craniofacial sutures.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2011年第5期522-525,共4页
West China Journal of Stomatology
基金
云南省自然科学基金资助项目(2002C0023R)
关键词
Ⅲ类错
磁力矫治器
颅面部骨缝
class Ⅲ malocclusion
magnetic appliance
craniofacial sutures
