摘要
目的:观察甘精胰岛素联合瑞格列奈治疗老年2型糖尿病的疗效。方法:89例老年2型糖尿病患者采用甘精胰岛素和瑞格列奈联合治疗,观察治疗3个月后的空腹血糖(FBG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)、空腹C肽(FCP)、餐后C肽(PCP)含量变化和低血糖反应。结果:与治疗前比较,治疗3个月后患者的FBG、2hPG、HbA1c水平均明显下降(P<0.05),FCP、PCP均升高。结论:甘精胰岛素联合瑞格列奈治疗老年2型糖尿病安全有效。
Objective：To investigate the efficacy of insulin glargine combined with repaglinide in old patients with type 2 diabetes.Methods：89 old patients with type 2 diabetes were treated with insulin glargine and repaglinide.The contents of the fasting blood glucose（FBG）,2-hour postprandial blood glucose（2hPG）,glycated hemoglobin（HbA1c）,fasting blood C-peptide（FCP）,postprandial blood C-peptide（PCP） and hypoglycemia were determined at 3-month post-Ramadan.Results：The contents of FBG,2hPG as well as HbA1c lowered（P〈0.05） at 3-month post-Ramadan,meanwhile,the contents of FCP,PCP increased.Conclusion：The results of this pilot study indicate that insulin glargine plus repaglinide regimen is effective and safe for old patients with type 2 diabetes.
出处
《中国当代医药》
2011年第28期57-58,共2页
China Modern Medicine
