摘要
目的:评价盐酸法舒地尔注射液治疗不稳定型心绞痛的临床疗效。方法:将86例不稳定型心绞痛患者随机分为对照组和治疗组,对照组43例,予以常规治疗,包括常规休息、吸氧、硝酸酯类、阿司匹林、氯吡格雷、低分子肝素及调脂药等常规治疗,心绞痛发作时舌下含服硝酸甘油片。治疗组43例,常规治疗外加盐酸法舒地尔注射液,静脉输注,2次/d,每次30mg。两组均治疗14d。观察评价两组的治疗前后48h内心绞痛发作情况和治疗效果。结果:心绞痛在治疗前后48h内发作情况,同组比较和两组比较,差异均有统计学意义(P<0.05);治疗组心绞痛症状改善总有效率为93.02%,明显优于对照组的58.14%。两者比较,差异有统计学意义(P<0.05)。结论:盐酸法舒地尔注射液治疗不稳定型心绞痛疗效确切。
Objective：To evaluate the clinical curative effect of hydrochloride fasudil in unstable angina pectoris.Methods：86 patients with unstable angina pectoris were randomly divided into control group and treatment group,the control group 43 cases were given routine treatment,included regular rest,oxygen,nitric acid ester,aspirin,clopidogrel,low molecular heparin and lipid conventional medicine treatment,angina tongue when including nitroglycerin piece.The treatment group 43 cases were given routine therapy plus hydrochloride fasudil,intravenous injection,two times a day,each time 30 mg.Both groups treatment for 14 days.Angina and therapeutic effect within 48 h before and after treatment were observed and evaluated.Results：Angina in 48 h before and after treatment within the same group,compared and attack two groups of comparisons were significant（P〈0.05）;the total effective rate of angina symptoms improvment in the treatment group was 93.02%,which was significantly better than the 58.14% of control group,both comparative differences was significant（P〈0.05）.Conclusion：The effect of hydrochloride fasudil in treatment of unstable angina symptoms is well.
出处
《中国当代医药》
2011年第28期44-45,共2页
China Modern Medicine
