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联合用药孕前干预D2聚体升高型复发性流产的临床研究 被引量:4

Clinical research of combination pregnant increased body type gather intervention D2 recurrent miscarriage
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摘要 目的:研究探讨小剂量阿司匹林联合维生素E孕前干预D2聚体升高型复发性流产的临床疗效观察。方法:收集本院2008年1月~2010年1月入诊的70例有2次以上流产病史、D2聚体升高大于正常值的妇女,在计划孕前3个月口服小剂量阿司匹林50~75mg/d联合维生素E200mg/d,观察并记录复发性流产的发生情况。与同期41例无孕前干预的患者再次复发流产相比较。结果:两组患者比较,其中观察组进行孕前小剂量阿司匹林联合维生素E干预D2聚体升高型复发性流产率(22.9%)明显低于对照组非药物干预的患者(51.2%)(P<0.05),差异有统计学意义。结论:小剂量阿司匹林联合维生素E孕前干预D2聚体升高型复发性流产临床疗效显著,能有效降低临床复发性流产的发生率,临床上值得推广。 Objective:To study the low-dose aspirin joint vitamin E pregnant intervention polymeric D2 increased recurrent miscarriage of the clinical curative effect of observation.Methods:Collection in January 2008-January 2010 of 70 cases of middle-class diagnosis had 2 or more times a history of abortion,polymer,greater than normal increase D2 the women in the plan,three months before childbirth oral low-dose aspirin 50 to 75 mg/day joint vitamin E 200 mg/day,observe and record the happening of recurrent miscarriage.The same period and 41 cases without the intervention of pregnant patients relapse again abortion in comparison.Results:Two groups of patients,including observation group was pregnant low-dose aspirin joint vitamin E intervention D2 polymer,recurrent miscarriage rate increase type(22.9%) was much lower than those of the control group the drug intervention of thepatients(51.2%)(P〈0.05),a statistically significant difference.Conclusion:Low-dose aspirin joint vitamin E pregnant intervention polymeric D2 increased recurrent miscarriage of clinical curative effect is distinct,can effectively reduce the incidence,clinical recurrent miscarriage clinical worth promoting.
出处 《中国当代医药》 2011年第28期28-29,共2页 China Modern Medicine
关键词 小剂量阿司匹林 维生素E 孕前干预 D2聚体 复发性流产 Low-dose aspirin Vitamin E Pregnant intervention D2 polymer Recurrent miscarriage
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