摘要
目的探讨女性免疫性不孕患者的综合治疗效果。方法对原发及继发不孕的妇女血清进行抗精子抗体（ＡＳＡｂ）、抗卵巢抗体（ＡＯＡｂ）、抗内膜抗体（ＥＭＡｂ）、抗绒毛膜促性腺激素抗体（ｈＣＧＡｂ）的检测，发现其阳性率分别为：２５．８８％、２２．８６％、３２．８１％、２３．６１％。采用地塞米松、维生素Ｅ、维生素Ｃ进行周期性治疗，３个周期为１疗程。结果１疗程后，４种抗体转阴率均可达９０％以上，妊娠率平均达３０％。结论皮质激素可以减少或消除免疫性不孕患者血清中抗体对妊娠各环节的影响，从而达到治疗不孕的目的。
Objective To investigate the treatment for immunologic infertility. Methods Serum antisperm antibody, anti ovarian antibody, anti endometrial antibody and anti hCG antibody in 1 020 female patients with primary or secondary infertility were tested. Patients were treated with dexamethasone, vitamin E and vitamin C for 3 cycles consecutively as one course. Results The detective rates of the above antibodies were 25.88%, 22.86%, 32.81% and 23.61% respectively. After one course of treatment, the disappearance rates of the antibodies mentioned were over 90%, and the average pregnancy rate was up to 30%. Conclusion Corticosterocls may reduce or even eliminate the effects of the immune factors on infertility.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1999年第4期234-236,共3页
Chinese Journal of Obstetrics and Gynecology
