摘要
目的分析新疆乌鲁木齐地区汉族与维吾尔族50岁以上人群血清25羟维生素D3水平差异,探讨其与骨质疏松症的关系。方法年龄50岁以上并完成血清骨转化指标及骨密度测定患者1 223例,汉族882例,维吾尔族341例。分析2个民族年龄、骨密度、血清25羟维生素D3及血清钙、磷水平的差异。结果汉族和维吾尔族原发性骨质疏松检出率比较差异无统计学意义(P>0.05);2个民族血清钙、磷水平在有无骨质疏松上差异无统计学意义(P>0.05);骨密度正常者,维吾尔族25羟维生素D3水平(30.19±19.67)nmol/L较汉族(48.50±27.97)nmol/L低(P<0.01);骨质疏松者,维吾尔族血清25羟维生素D3水平(31.82±20.79)nmol/L较汉族(47.41±26.56)nmol/L低(P<0.01);年龄与血清25羟维生素D3水平无相关性(r=0.007,P=0.817)。结论不同民族间血清25羟维生素D3水平有差异,其差异与骨质疏松无关。
Objective To study the differences of serum 25-hydroxy vitamin D3 level in Han and Uygur patients older than years 50 in Urumqi area,and to study its relationship with osteoporosis.Methods A total of 1223 patients older than 50 were detected biochemical markers of bone resorption and formation and bone mineral density,in which 882 were from Han nationality and 341 were from Uygur nationality.The differences in age,bone mineral density,serum 25-hydroxy vitamin D3,and serum Ca and P levels were analyzed and compared between two groups.Results There were no significant differences in detection rate of osteoporosis,or serum Ca and P levels between two groups（P0.05）.In patients with normal bone mineral density,serum 25-hydroxy vitamin D3 level was（48.50±27.97）nmol/L in Han patients,and（30.19±19.67）nmol/L in Uygur patients,which showed a significant difference between two groups（P0.01）.In patients with osteoporosis,serum 25-hydroxy vitamin D3 level was（47.41±26.56）nmol/L in Han patients,and（31.82±20.79）nmol/L in Uygur patients,which showed a significant difference between two groups（P0.01）.The age was not correlated with 25-hydroxy vitamin D3 level.Conclusion The serum 25-hydroxy vitamin D3 levels are different between Han and Uygur nationality,which is not correlated with oteoporosis.
出处
《中华实用诊断与治疗杂志》
2011年第10期950-952,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
民政部"十一.五"课题子课题(民人教科字(2007)18-1-39)
