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血清同型半胱氨酸和SOD水平与急性脑梗死的相关性研究 被引量:10

The correlation among serum homocysteine,SOD levels and acute cerebral infarction
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摘要 目的:探讨血浆同型半胱氨酸(HCY)及超氧化物歧化酶(SOD)水平与急性脑梗死的关系。方法:测定156例急性脑梗死患者血浆HCY及SOD水平,并进行相关分析。结果:急性脑梗死患者治疗前血清Hcy高于正常对照组(P<0.05),而SOD水平则低于正常对照组(P<0.05),且两者水平与梗死灶面积呈显著相关(P<0.05),经治疗2周后HCY及SOD水平与正常对照组比较差别无统计学意义(P>0.05)。结论:检测急性脑梗死患者血清Hcy和SOD水平的变化对判断病情和评价疗效均具有重要的临床价值。 Objective:To investigate the changes of serum homocystein(Hcy)and Superoxide dismutase(SOD) levels after treatment in patients with acute cerebral infarction(ACI).Methods:Before and after treatment,serum SOD and Hcy levels in156 patients with ACI as well as 40 controls were detected.Results:Before treatment,serum Hcy and SOD levels were significantly different in the patients with ACI compared with those in controls(P〈0.05),Moreover,both levels were significantly correlated with the size of the infarction(P〈0.05).After treatment for two weeks,the serum Hcy,SOD levels were not significantly different from those in controls(P〈0.05).Conclusion:Detection of serum Hcy and SOD levels may be valuable means for predicting the prognosis for patients with ACI.
出处 《中国卫生检验杂志》 CAS 2011年第10期2463-2464,共2页 Chinese Journal of Health Laboratory Technology
关键词 急性脑梗死 同型半胱氨酸 超氧化物歧化酶 Acute cerebral infarction Homocysteine(Hcy) Superoxide dismutase(SOD)
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