摘要
目的探讨负压封闭引流技术（VSD）在重度糖尿病足坏疽（DFG）治疗中的临床疗效及适应证。方法随机选取60例符合Wagner分级3～5级的DFG患者，使用VSD技术治疗创面，即VSD治疗组，采用回顾性对照研究的方法，对1年前采用创面常规引流方法治疗DFG的患者62例进行对照分析，即常规治疗组，观察创面愈合时间、换药次数、转归（治愈率）、平均住院时间及住院总费用等。结果VSD组与常规治疗组比较创面愈合时间[（30．5±6．8）d与（53．8±5．5）d，t=2．636]、换药次数[（15．0±4．7）次与（29．5±6．1）次，t=2．374]、治愈率[96．7％（58／60）与87．1％（54／62），χ2=9．93]、平均住院时间[（20．1±3．5）d与（36．5±4．6）d，t=2．564]、总住院费用[（20155．6±153．8）元与（41465．5±146．6）元，t=2．873]，差异均有统计学意义（P均〈0．05）。结论VSD治疗重度DFG疗效好，明显缩短创面愈合时间，提高治愈率，明显缩短住院时间，降低住院费用，是治疗DFG创面的有效方法。
Objective To investigate the clinical effects and indications of the vacuum sealing drainage （VSD） in the treatment of severe diabetic foot gangrene. Methods We randomly recruited 60 cases,who had suffered from diabetic foot gangrene （DFG） at the grade of 3 -5, according to Wagner scale into VSD treatment groups and treated them with VSD methods. At the same time, 62 DFG cases who had given routine drainage treatment one year ago were retrospectively analyzed as control group. The observed items included the wound healing time, number of dressing, outcome of treatment （ healing rate）, the average days in hospital, total expenses of hospitalization and so on. Results The wound healing time of VSD treatment group and routine treatment group were （ 30. 5 ± 6. 8 ） days and （ 53.8 ± 5.5 ） days, respectively （ t = 2. 636, P 〈 0. 01 ）. The numbers of dressing were（ 15.0± 4. 7） days and （29. 5± 6. 1 ） days , respectively （ t = 2. 374, P 〈 0. 01 ）. The healing rates were 96. 7% （58/60） and 87. 1% （54/62）, respectively （ P 〈 0. 01 ）. The average period in hospitalization were （20. 1 ± 3.5 ） days and （ 36. 5± 4. 6） days, respectively （ t = 2. 564, P 〈 0. 01 ）. Total expenses of hospitalization were （ 20 155.6 ±153.8 ） yuan RMB and （41 465.5±146. 6） yuan RMB, respectively （ t = 2. 873, P 〈 0. 01 ）. All the differences were statistically significant. Conclusion The VSD method is effective for the treatment of severe diabetic foot gangrene （DFG）. It is able to reduce the time of wound healing significantly, increase the healing rate, shorten the hospitalization period and cut the general expenses during hospitalization. It＇s an effective method for the treatment of DFG.
出处
《中国综合临床》
2011年第10期1066-1069,共4页
Clinical Medicine of China
关键词
糖尿病足坏疽
负压封闭引流
Diabetic foot gangrene
The vacuum sealing drainage
