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中青年腹型肥胖男性睾酮与颈动脉内膜中层厚度的相关性 被引量:1

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摘要 目的探讨中青年腹型肥胖男性血清睾酮与颈动脉内膜中层厚度(IMT)相关性。方法选取20~50岁男性为研究对象,其中腰围刍90cm男性51例为腹型肥胖组,腰围〈90cm男性34例为对照组。结果腹型肥胖组血清睾酮浓度低于对照组[(5.99±1.56)μg/L与(7.52±2.13)μg/L,t=3.792,P〈0.01)],IMT高于对照组[(0.74±0.10)mm与(0.67±0.05)mm,t=3.741,P〈0.01)]。IMT与体重指数(r=0.426,P=0.000)、腰围(r=0.477,P=0.000)、收缩压(r=0.215,P=0.048),甘油三酯(r=0.244,P=0.024),Homa胰岛素抵抗指数(r=0.295,P=0.006)和睾酮(r=-0.255,P=0.018)存在单变量相关。以IMT为因变量,行多元线性回归显示,腰围(B=0.004,P=0.000)被引入方程。结论中青年腹型肥胖男性存在血清睾酮浓度及IMT改变,血清睾酮与IMT呈负相关趋势,但两者的关系有待进一步研究证实。
出处 《中国综合临床》 2011年第10期1060-1062,共3页 Clinical Medicine of China
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