摘要
目的探讨不同严重程度的慢性阻塞性肺疾病(COPD)急性加重期患者痰培养菌种分布及细菌耐药情况。方法对新疆自治区中医院呼吸科2008年1月至2009年12月收治的COPD急性加重期患者176例,其中99例痰培养结果阳性进行回顾性分析。结果 COPD患者肺功能损伤加重时常伴随肠杆菌、不动杆菌、假单胞菌的高检出率,耐药金黄色葡萄球菌的检出率随着肺功能的损害而增加,而当肺功能相对较好时,则以肺炎链球菌、流感嗜血杆菌和肺炎克雷伯杆菌为主。结论不同严重程度的慢性阻塞性肺疾病急性加重期患者痰培养菌种分布差异明显,应合理选择抗菌药物。
Objective To investigate the bacteria distribution in sputum bacteria culture and drug resistance in patients with acute exacerbations of chronic obstructive pulmonary disease（COPD）. Methods From February 2008 to December 2009,176 pa tients who has been given therapy due to COPD in acute exacerbation stage were selected in Department of respiratory in Tradition al Chinese medicine hospital of Xinjiang region. Results In COPD patients,with the exacerbation of lung damage,enteric bacilli, Acinetobacte, pseudomonas and drug resistant staphylococcus aurous had high detection rate. Patients with the light degree of func- tional impairment presented a higher probability of streptococcus pneumoniae, hemophilies influenzaemonas and lebsiella pneumoni ae in significant concentrations in sputum. Conclusion There are significantly differences of distribution of the bacteria in sputum bacteria culture in different degrees of severity in patients with acute exacerbations of chronic obstructive pulmonary disease （COPD）. Antibiotics should be choiced properly.
出处
《重庆医学》
CAS
CSCD
北大核心
2011年第30期3063-3065,共3页
Chongqing medicine
关键词
肺疾病
慢性
阻塞性
细菌
药用制剂
pulmonary disease, chronic obstructive
bacteria
pharmaceutical preparations
