摘要
目的:探讨磁共振动态增强曲线、DWI及其联合应用对乳腺病变的定性诊断价值。方法:搜集乳腺疾病患者42例,全部行动态增强扫描及DWI(b=1000s/mm2),42例均获病理证实,其中良性21例(24个病灶),恶性21例(23个病灶)。统计比较动态增强曲线、DWI及两者联合诊断乳腺病变的敏感度、特异度及诊断符合率。结果:ROC曲线确定的ADC诊断阈值为1.195×10-3mm2/s。动态增强曲线、DWI及两者联合诊断乳腺癌的敏感度分别为100%、91.3%、95.6%,特异度分别为66.7%、75%、87.5%,诊断符合率分别为83%、83%、91.5%。结论:磁共振动态增强曲线联合DWI对诊断乳腺病变有较高的诊断符合率及特异度,对乳腺病变的定性诊断具有重要价值。
Objective：To evaluate the sensitivity,specificity and accuracy of dynamic contrast enhanced imaging,diffusion weighted imaging and combination of the two methods in the charaterization of breast lesion.Methods：47 lesions of 42 patients were acquired with histopathological demonstration,of which 23 were malignant and 24 were benign.All lesions were examined with dynamic contrast enhanced MRI and DWI（b=1000s/mm2）.Using integral method and statistics the sensitivity,specificity and accuracy of the dynamic enhancement curve,DWI and combination of the two methods in the diagnosis of breast lesions were comparted.Results：The threshold between benign and malignant lesions was 1.195×10-3mm2 /s by ROC curve.The sensitivity of dynamic enhancement curves,DWI and combination of both for diagnosis of breast lesions was 100%,91.3% and 95.6% respectively,specificity was 66.7%,75%,87.5% respectively and accuracy was 83%,83%,91.5% respectively.Conclusion：The specificity and accuracy of combination of dynamic contrast-enhanced MRI and DWI was higher in the diagnosis of breast lesions than either exam method,that is very helpful for characterization of breast lesions.
出处
《放射学实践》
北大核心
2011年第9期957-960,共4页
Radiologic Practice
关键词
乳腺肿瘤
磁共振成像
ROC曲线
Breast neoplasms
Magnetic resonance imaging
ROC curve
