摘要
从云南产小百部(Asparagus filicinus Buch.-Ham)的根中分离到四个甾体皂甙,经光谱分析和化学降解,确定了结构,其中三个为新化合物,分别命名为小百部甙A(Ⅰ),小百部甙B(Ⅱ)和小百部甙C(Ⅲ)。另一个为已知皂甙Asp-Ⅳ的22-甲氧基化物(Ⅳ)。此外还分离到β-蜕皮甾酮(β-ecdysone,Ⅴ)。
Three new steroidal saponins, aspafilioside A,B and C together with a known saponin 22-methoxy ASP-Ⅳ and β-ecdysone were isolated from the root of Asparagus fiticinus Buch.-Ham. (Chinese name as xiao-bai-bu), a folk medicine of the minorities in Yunnan Province, China, used for the treatment of bronchitis, pneumonitis and cough. Their structures were established as sarsasapogenin-3-O-β-D-xy lopyranosyl (1→4)-β-D-glucopyranoside (Ⅰ), sarsasapogenin-3-O-β-D-xylopyranosyl (1→4) [α-L-arabinopyranosyl (1→6)]-β-D-glucopyranoside (Ⅱ)and (25S)-5β-furost-3β, 22,26-triol-3-O-β-D-xylopyranosyi (1→4) [α-L-arabinopyranosyl (1→6)]-β-D-glucopyranoside-26-O-β-D-glucopyranoside (Ⅲ) by spectral and chemical methods.
出处
《药学学报》
CAS
CSCD
北大核心
1990年第7期509-514,共6页
Acta Pharmaceutica Sinica
关键词
小百部
甾体皂甙
成分
Asparagus filicinus Bunch. -Ham.
Steroidal saponin
Sarsasapogenin
Aspafilioside A
Aspafilioside B :Aspafilioside C
