摘要
目的总结分析原发性胃肠道恶性淋巴瘤（PGIML）的内镜下特征及诊断要点，进一步提高该病的诊断阳性率，为临床治疗提供依据。方法回顾性分析2004—2009年诊治的67例PGIML患者的临床资料。结果PGIML临床症状缺乏特异性。主要表现为腹痛、黑便、腹部包块。胃是最常见的发生部位，达55．8％（37／67）。黏膜表面呈肿块结节是PGIML最常见的内镜表现。内镜活检诊断PGIML的阳性率为68．7％（46／67）。67例均为非霍奇金淋巴瘤。免疫分型以B细胞为主，为50例。30例为黏膜相关淋巴组织（MALT）淋巴瘤。结论PGIML早期诊断较困难，可采取多种诊断手段综合诊断，手术治疗作用尚未肯定，还需进一步随访观察。
Objective To summarize the endoscopic characteristics of Primary Gastrointestinal Malignant Lymphoma （PGIML） and increase the diagnostic accuracy of this method to aid the clinical treatment. Methods The clinical data of 67 cases with PGIML from 2004 to 2009 were studied retrospectively. Results PGIML lacked specific clinical symptoms. The main clinical symptoms were abdominal pain, melena and abdominal mass. In our study, most PGIML（ 37/67,55.8% ） were detected in stomach. Nodular appearance of mucosal surface was the most common endoscopic finding. The positive rate of endoscopic biopsy for the diagnosis of PGIML was 68.7 % （46/67 biopsy cases）. All cases had Non-Hogkin Lymphoma （NHL）. The most common immunophenotype was B-cell majority （50/67）. Thirty cases had MALT. Conclusion It is hard to diagnose PGIML at early stage, combination of various diagnosis tests should be considered to solve this problem. The effectiveness of surgery on PGIML should be further confirmed by prospective randomized clinical trials.
出处
《中国综合临床》
2011年第9期953-955,共3页
Clinical Medicine of China
关键词
恶性淋巴瘤
胃肠道
内镜诊断
Malignant lymphoma
Gastrointestinal tract
Endoscopic diagnosis
