期刊文献+

西番莲属植物的抗焦虑活性成分及其作用机制研究进展 被引量:10

Progress on the Research of Anxiolytic Ingredients and the Mechanisms of Passiflora Linn
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摘要 国外普遍将西番莲属植物用于治疗焦虑等疾病,近年国内外对其活性成分和作用机制进行了研究。认为γ-氨基丁酸(GABA)、亲脂性物质、苯并黄酮、白杨素、β-咔啉吲哚生物碱等是西番莲属植物中具有抗焦虑活性的成分,其作用机制涉及到GABA-苯二氮受体复合体的作用、芳香酶抑制作用、单胺氧化酶抑制作用等。 Passiflora Linn has been widely used on the treatment of anxiety. Its active ingredients and the action mechanism has been studied by researchers home and abroad. These studies show that the antianxiety compounds of Passiflora Linn are:γ-aminobutyric acid(GABA), lipophilic compounds, benzoflavone(BZF), chrysin, β-Carboline and indole alkaloids. Its functional mechanism consists of the effect on GABA-benzodiazepines receptor compounds, the inhibition of aromatase and monoamine oxidase.
出处 《食品与药品》 CAS 2011年第9期354-357,共4页 Food and Drug
基金 广州市基础研究计划项目(2005J1-C0352) 广东省中医药局科研课题(2010253)
关键词 西番莲属 抗焦虑 活性成分 作用机制 Passiflora Linn anxiolytic effect active ingredient mechanism
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参考文献25

  • 1周玉娟,谈锋,邓君.西番莲属植物的研究进展[J].中国中药杂志,2008,33(15):1789-1793. 被引量:62
  • 2Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incamata Linneaus [J]. J Ethnopharmacol, 2001, 78:165-170.
  • 3Carratu B, Boniglia C, Giammarioli S, et al. Free aminoacids in botanicals and botanical preparations[J]. Science Food, 2008, 73 (5):323-328.
  • 4Elsas S M, Rossi D, Raber J, et al. Passiflora incarnata L. (passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method [J]. J Phymed, 2010, 3(2):1.
  • 5Gustavo P, Franis N, Daniela V, et al. Participation of GABA- benzodiazepine receptor complex in the anxiolytic effect of PassiJTora alata curtis (Passifloraceae)[J]. Lat Am J Pharm, 2008, 27(6): 845-851.
  • 6Pollyanna C, Alberto H, Jair C, et al. Possible anxiolytic effect of two extracts of Passiflora quadrangularis L in experimental models[J]. Phytother Res, 2007, 21: 481-484.
  • 7Soulimani R, Younos C, Jarmouni S, et al. Behavioural effects of Passiflora incarnata L.and its indole alkaloid and flavonoid derivatines and maltol in mouse[J]. J Ethnopharmacol, 1997, 57:11-20.
  • 8Grundmann O, Wang J, Gerard P, et al. Activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system [J]. Planta Med, 2008, 74:1769-1773.
  • 9Lolli L, Sato C, V C, et aL Possible involvement of GABAA- benzodiazepine receptor in the anxiolytic-like effect induced by Passiflora actinia extracts in mice [J]. J Ethnopharmacol, 2007, 111:308-314.
  • 10Dhawan K, Dhawan S, Sharma A. Passiflora: a review update[J]. J Ethnopharmacol, 2004, 94:1-23.

二级参考文献40

  • 1吴均秀.浅谈西番莲及其发展前景[J].广西热作科技,1994(1):43-46. 被引量:15
  • 2陈惠芳.植物药数据库[J].国外医药(植物药分册),2005,20(6):270-273. 被引量:10
  • 3Hickey M, King C. 100 Families of flowering plants[ M]. Cambridge: Cambridge University Press, 1988:130.
  • 4Pereira Cintia A M,Vilegas Janete H Y. Chemical and pharmacological constituents of Passiflora alata Dryander, Passiflora edulis Sims and Passiflora incarnata Linn [ J ]. Rev Brasileira Plantas Med, 2000,3(1) :1.
  • 5Dhawan K, Dhawan S, Sharma A. Passiflora: a review update [J]. J Ethnopharmacol, 2004,94:1.
  • 6Mareck U, Herrmann K, Galensa R, et al. The 6-C-chinovoside and 6-C-fucoside of luteolin from Passiflora edulis [ J ]. Phytochem, 1991,30(10) :3486.
  • 7Kidoey L, Nygaard A M,Andersen O M, et al. Anthocyanins in fruits of Passiflora edulis and P. suberosa[ J]. J Food Compos Anal, 1997,10( 1 ) :49.
  • 8Chang Y W, Su J D. Antioxidant activity of major anthocyanins from skins of passion fruit [ J]. Chin Inst Food Sci Technol, 1998,25 (5) :651.
  • 9Lohdefink V J, Kafing H. Zur frage des vorkommens yon harmanalkaloiden in Passiflore[ M]. Planta Med, 1974,25:101.
  • 10Narain N, Bora P S. Post-harvest changes in some volatile flavor constituents of yellow passion fruit ( Passiflora edulis f. flavicarpa) [J]. J Sci Food Agric, 1992,60(4) :529.

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