摘要
国外普遍将西番莲属植物用于治疗焦虑等疾病,近年国内外对其活性成分和作用机制进行了研究。认为γ-氨基丁酸(GABA)、亲脂性物质、苯并黄酮、白杨素、β-咔啉吲哚生物碱等是西番莲属植物中具有抗焦虑活性的成分,其作用机制涉及到GABA-苯二氮受体复合体的作用、芳香酶抑制作用、单胺氧化酶抑制作用等。
Passiflora Linn has been widely used on the treatment of anxiety. Its active ingredients and the action mechanism has been studied by researchers home and abroad. These studies show that the antianxiety compounds of Passiflora Linn are:γ-aminobutyric acid(GABA), lipophilic compounds, benzoflavone(BZF), chrysin, β-Carboline and indole alkaloids. Its functional mechanism consists of the effect on GABA-benzodiazepines receptor compounds, the inhibition of aromatase and monoamine oxidase.
出处
《食品与药品》
CAS
2011年第9期354-357,共4页
Food and Drug
基金
广州市基础研究计划项目(2005J1-C0352)
广东省中医药局科研课题(2010253)
关键词
西番莲属
抗焦虑
活性成分
作用机制
Passiflora Linn
anxiolytic effect
active ingredient
mechanism