摘要
目的探讨人类巨细胞病毒初期感染与冠心病发生发展的关系。方法用捕获ELISA法检测血清HCMV—IgM，酶法检测血脂4项，免疫比浊法检测C-反应蛋白（CRP），并进行比较。结果冠心病组（61例）、健康对照组（44例）和其他疾病组（48例）的HCMV—IgM阳性率分别为8．20％、2．27％和4．17％，冠心病组与对照组之间无统计学差异（P〉0．05）；冠心病组血脂4项和CRP均高于健康对照组，有统计学差异（P〈0．05）。结论尚不能认为冠心病与巨细胞病毒初期感染有关。
Objective To investigate the correlation between the occurrence and development of coronary artery disease（CAD） and HCMV incipient infection. Methods The levels of HCMV - IgM were detected in serum samples of 61 CAD patients,44 healthy individuals and 48 patients without cardiovascular disease and diabetes mellitus by using enzyme -linked immunosorbent assay（ELISA） ,and four indexes of lipoid and C reactive protein（CRP） were detected in serum at the same time. Results The positive rates of HCMV - IgM in CAD group, heathlthy individuals and control group without cardiovascular disease and diabetes mellitus were 8.20% （ 5/61 ） , 2.27% （ 1/44 ） and 4.17% （2/48）,respectively. There were no significant difference between the CAD group with control group（ x^2 = 1. 970,P = 0. 374）. The level of four indexes of lipoid and C reactive protein （CRP） of CAD group were higher than control group（P 〈 0.05）. Conclusion The present study does not suggest that coronary artery disease is associated with HCMV incipient infection.
出处
《医学新知》
CAS
2011年第4期272-274,共3页
New Medicine
关键词
巨细胞病毒
IGM
冠心病
感染
Human cytomegalovirus
IgM
Coronary atherosclerotic heart disease
Infection
