摘要
髋关节的正常生长发育需要髋臼、股骨近端、关节周围韧带、血管、神经以及肌肉的协调生长共同完成。它由复杂的基因网络调控,同时受环境、生物因素的影响。现从出生前髋关节发育、出生后髋关节发育、髋关节的血管神经支配以及髋关节形成的分子机制等方面对髋关节的正常生长发育进行全面系统的回顾,为临床研究髋关节疾病,如发育性髋关节发育不良等提供理论基础。
The normal hip development is the result of a complicated balance of acetabulum,proximal femur,ligaments,vasculature,nerves,and muscles.The program of hip development is controlled by complicated celluar events which are influenced by environmental and biologic factors.The systemic review is to show the following aspects of the normal hip development,the prenatal development,postnatal development,the arterial supply and innervation of the hip,and the cell signaling in intrauterine hip joint development.Understanding the sequential steps of the hip′s development is critical to elucidate the pathobiologic mechanisms of hip disease and deformity,such as hip dysplasia.
出处
《医学综述》
2011年第16期2401-2404,共4页
Medical Recapitulate
基金
国家自然科学基金面上项目(30901570)
关键词
髋关节
生长发育
股骨近端
髋臼
Hip joint
Development
Proximal femur
Acetabulum
