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埃兹蛋白与肿瘤转移关系的研究进展 被引量:2

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摘要 转移是恶性肿瘤的主要生物学特征,是导致肿瘤患者死亡的主要原因。关于肿瘤的发生机制的研究已取得重大突破,但对于肿瘤细胞转移的具体机制仍不甚清楚。这篇综述的目的是提供一个已被证实参与肿瘤发生、转移的分子:埃兹(Ezrin)蛋白,作为埃兹蛋白/根蛋白/膜突蛋白(ezrin/radixin/moesin,ERM)蛋白家族的成员之一,是一种细胞膜与细胞骨架的连接蛋白,是将细胞外信号传递到骨架蛋白的重要联系分子,参与细胞黏附和运动,并参与细胞凋亡和吞噬。
作者 张庆飞 杨兵
出处 《临床医药实践》 2011年第9期684-686,共3页 Proceeding of Clinical Medicine
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  • 1Jemal A,Siegel R,Ward E,Murray T,Xu J,Smigal C,Thun MJ.Cancer statistics, 2006. CA A Cancer Journal for Clinicians . 2006
  • 2Benjamin Bruce,Gaurav Khanna,Ling Ren,Goran Landberg,Karin Jirstr?m,Charles Powell,Alain Borczuk,Evan T. Keller,Kirk J. Wojno,Paul Meltzer,Kristin Baird,Andrea McClatchey,Anthony Bretscher,Stephen M. Hewitt,Chand Khanna.Expression of the cytoskeleton linker protein ezrin in human cancers[J]. Clinical & Experimental Metastasis . 2007 (2)
  • 3David Sarrió,Socorro María Rodríguez-Pinilla,Ana Dotor,Francisco Calero,David Hardisson,José Palacios.Abnormal ezrin localization is associated with clinicopathological features in invasive breast carcinomas[J]. Breast Cancer Research and Treatment . 2006 (1)
  • 4Bockman DE,Guo J,Büchler P,Müller MW,Bergmann F,Friess H.Origin and development of the precursor lesions in experimental pancreatic cancer in rats. Laboratory Investigation . 2003
  • 5García-Morales P,Gómez-Martínez A,Carrato A,Martínez- Lacaci I,BarberáVM,Soto JLet al.Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines. Molecular Cancer Therapeutics . 2005
  • 6Mallikarjuna K,,Pushparaj V,Biswas J,Krishnakumar S.Expression of epidermal growth factor receptor,ezrin, hepatocyte growth factor,and c-Met in uveal melanoma:an immunohistochemical study. Current Eye Research . 2007
  • 7Yeh TS,Tseng JH,Liu NJ,Chen TC,Jan YY,Chen MF.Significance of cellular distribution of ezrin in pancreatic cystic neoplasms and ductal adenocarcinoma. Archives of Surgery . 2005
  • 8Ogino W,Takeshima Y,Mori T,Yanai T,Hayakawa A,Akisue Tet al.High level of ezrin mRNA expression in an osteosarcoma biopsy sample with lung metastasis. Journal of Pediatric Hematology Oncology . 2007
  • 9Comoglio PM,Giordano S,Trusolino L.Drug development of MET inhibitors:targeting oncogene addiction and expedience. Nature Reviews Drug Discovery . 2008
  • 10Murai M,Shen X,Huang L,Carpenter WM,Lin CS,Silverman Set al.Overexpression of c-met in oral SCC promotes hepatocyte growth factor-induced disruption of cadherin junctions and invasion. International Journal of Oncology . 2004

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  • 1Liu XY,Yang JL,Chen LJ,et al. Comparative proteomics and correla- ted signaling network of rat hippocampus in the pilocarpine model of temporal lobe epilepsy[ J ]. Proteomics ,2008,8 ( 3 ) :582 - 603.
  • 2Sutula TP, Pitkanen A. More evidence for seizure-induced neuron loss:is hippocampal sclerosis both cause and effect of epilepsy [ J ]. Neurology ,2001,57(2) : 169 - 170.
  • 3Yang JW, Czech T, Felizardo M, et al. Aberrant expression of cytoskel- eton proteins in hippocampus from patients with mesial temporal lobe epilepsy[ J]. Amino Acids,2006,30(4) :477 -493.
  • 4Greene ND, Bamidele A, Choy M, et al. Proteome changes associatedwith hippocampal MRI abnormalities in the lithium pilocarpine-in- duced model of convulsive status epilepticus [ J]. Proteomies,2007,7 (8) :1336 -1344.
  • 5]Binder DK,Steinhauser C. Functional changes in astroglial cells in ep- ilepsy[ J ]. Glia ,2006,54 ( 5 ) :358 - 368.
  • 6Xu Z,Xue T,Zhang Z, et al. Role of signal transducer and activator of transcription-3 in up-regulation of GFAP after epilepsy[ J ]. Neuro- chem Res,2011,36(12) :2208 -2215.
  • 7林卫红,孟红梅,王赞,马涤辉,杨立彬,崔俐,张淑琴.杏仁核点燃大鼠海马区损伤与胶质纤维酸性蛋白的表达[J].吉林大学学报(医学版),2007,33(5):837-840. 被引量:1
  • 8谢丽,杨俊玲,张培莲.细胞骨架蛋白Ezrin的生物学特性[J].现代肿瘤医学,2009,17(1):171-173. 被引量:2
  • 9梁益,孙红斌,喻良,何保明,谢彦.锂-匹罗卡品致大鼠海马胶质纤维酸性蛋白的表达及意义[J].卒中与神经疾病,2009,16(5):280-283. 被引量:3
  • 10王家祥,穆鑫,孟庆磊,马威,张国锋.Ezrin蛋白、CD44、E-钙粘素与神经母细胞瘤转移的关系[J].中华小儿外科杂志,2011,32(6):410-413. 被引量:4

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