摘要
目的:探讨小青龙汤对支气管哮喘急性发作的临床疗效及可能机制。方法:患者随机分为常规治疗组和小青龙汤组,常规治疗组给予西医常规治疗,治疗组在常规治疗组的基础上加用小青龙汤,治疗前后进行疗效及肺功能、外周嗜酸性粒细胞(EOS)等指标比较。结果:两组患者治疗前后临床疗效及肺功能、EOS等均等到显著改善(P<0.05),小青龙汤组较常规治疗组疗效更佳,肺功能、EOS等指标改善更显著(P<0.05)。结论:小青龙汤能提高西医常规治疗对支气管哮喘急性发作的临床疗效,其机制可能与改善患者免疫紊乱,减轻嗜酸性粒细胞对肺组织浸润,减轻气道炎症,降低气道高反应有关。
Objective： To explore the clinical effect and possible mechanism of treating acute exacerbation of bronchial asthma in Xiaoqinglong decoction. Methods： Patients were randomly divided into common treatment group and Xiaoqinglong decoction group, in which, common treatment group applying Western medicine, based on that, treatment group plus Xiaoqinglong decoction, then compared their effects, lung function, EOS and so on before and after the treatment. Results： Clinical effects, lung function, EOS and so on in two groups＇ patients were obviously improved before and after the treatment （P〈0.05）. Xiaoqinglong decoction group was better than common treatment group, which lung function, EOS and so on were more improved （P〈0.05）. Conclusion： Xiaoqinglong decoction could improve the clinical effect of treating acute exacerbation of bronchial asthma in common Western medicine, which mechanism may have a relation with improving immune disorders, reducing eosinophil infiltration of lung tissue, reducing airway inflammation and reducing airway hyperresponsiveness.
出处
《中医临床研究》
2011年第15期22-23,共2页
Clinical Journal Of Chinese Medicine
关键词
支气管哮喘急性发作
临床疗效
伤寒论
Acute exacerbation of bronchial asthma
Clinical effect
Treatise on
