摘要
为探索血清肿瘤标志物CA72-4、MG-7在胃癌诊断中的意义,本文分别采用电化学发光法和免疫放射分析法(IR-MA)检测血清CA72-4及MG-7在53例胃癌患者、27例其它肿瘤患者、56例良性疾病患者及36名健康人中的含量,分析上述两种指标在胃癌诊断中的意义。结果显示,CA72-4在胃癌组和其它肿瘤组中的阳性率分别为86.8%和88.9%,含量较健康对照组高(P<0.05),但其在良性疾病组和健康对照组中也有一定的检出率(分别为32.1%、19.4%)。MG-7在胃癌组含量同样较健康对照组高(P<0.05),阳性率为52.8%,但MG-7在良性疾病组中检出率很低(3.6%),在健康对照组中无检出。CA72-4与MG-7联合检测在胃癌组和健康对照组中检出率分别为92.5%和19.4%。血清CA72-4、MG-7在胃癌诊断中具有重要作用。
To explore the diagnosis value of serum CA72-4 and MG-7 in patients with gastric carcinoma,serum CA72-4 and MG-7 in 53 patients with gastric carcinoma,27 patients with cancers out of stomach,56 patients with benign diseases and 36 healthy controls were detected by electrochemiluminescent and IRMA respectively.The results showed that the positive expression rates of CA72-4 in patients with gastric carcinoma and other cancers were 86.8% and 88.9% respectively.The serum concentrations of CA72-4 in patients with gastric carcinoma and other cancers were remarkably higher than in controls（P0.05）.The serum concentrations of MG-7 in patients with gastric carcinoma and other cancers were remarkably higher than in controls（P0.05）.The positive expression rate in patients with gastric carcinoma was 52.8%,3.6% in benign diseases,and no expression in controls.The positive expression rates of CA72-4 and MG-7 combination was 92.5% and 19.4% respectively in gastric carcinoma and healthy controls.The detection of serum CA72-4 and MG-7 play a very important role in the diagnosis of gastric carcinoma.
出处
《标记免疫分析与临床》
CAS
2011年第4期233-235,共3页
Labeled Immunoassays and Clinical Medicine
