摘要
目的通过观察"益气调血,扶本培元"组穴对正常健康老年人脑葡萄糖代谢的影响,为针刺效应和特异性研究提供影像学依据。方法选择10例正常老年人随机分为穴位组和非穴组。治疗组取膻中、中脘、气海、血海、外关、足三里穴,对照组取上述穴位旁开的非经非穴点进行针刺研究,每天1次,每星期5次,连续进行8星期。治疗前和治疗8星期后所有患者均接受正电子发射型计算机断层显像(PET)脑功能成像检查,观察针刺前后感兴趣脑区葡萄糖代谢变化特征。结果针刺8星期后穴位组双侧额叶和双侧海马区葡萄糖代谢较针刺前均明显升高(P<0.05),非穴组针刺前后无明显变化;两组比较8星期后治疗组双侧额叶和左侧颞叶葡萄糖代谢均明显高于非穴组(P<0.05)。结论 "益气调血,扶本培元"组穴可以提高正常老年人认知相关脑区葡萄糖代谢,且具有显著的腧穴特异性。
Objective To provide an image basis for the effect and specificity of acupuncture by investigating the effect of qi-tonifying,blood-regulating and constitution-strengthening acupuncture points on cerebral glucose metabolism in healthy elderly persons.Methods Ten healthy elderly persons were randomly allocated to acupoint and non-acupoint groups.In the acupoint group selected were points Danzhong（CV 17）,Zhongwan（CV12）,Qihai（CV6）,Xuehai（SP10）,Waiguan（TE5） and Zusanli（ST36） and in the non-acupoint group,non-meridian points beside the above acupoints.Acupuncture research was made once daily,5 times a week,for 8 consecutive weeks.Positron emission tomography（PET） was performed for brain function imaging in all the persons before and after 8 weeks of treatment.The characteristics of changes in glucose metabolism in a brain region of interest were observed before and after acupuncture.Results After 8 weeks of treatment,glucose metabolism in bilateral frontal lobes and hippocampal regions increased significantly in the acupoint group（P0.05） and did not change significantly in the non-acupoint group as compared with before acupuncture.After 8 weeks of treatment,glucose metabolism in bilateral frontal lobes and hippocampal regions was significantly higher in the acupoint group than in the non-acupoint group（P0.05）.Conclusions Qi-tonifying,blood-regulating and constitution-strengthening acupuncture points can increase glucose metabolism in cognitive regions of the brain in healthy elderly persons and have marked acupoint specificity.
出处
《上海针灸杂志》
2011年第8期571-573,共3页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家自然科学基金资助项目(30630074)
关键词
针刺
正电子发射型计算机断层显像
萄萄糖代谢
脑老化
Acupuncture
Positron emission computerized tomography
Glucose metabolism
Brain ageing
