摘要
目的探究脑血流量(CBF)、纤维蛋白原(Fig)、红细胞压积(Hct)、血小板电泳时间对急性脑梗死预后的影响。方法 90例急性脑梗死患者按照临床结局恢复情况分为治愈组、缓解组及死亡组,比较分析各组患者急性期和恢复期中的Fig、Hct、血小板电泳时间和CBF。结果脑梗死各组患者急性期CBF下降,Fig升高及血小板电泳时间延长;缓解组和死亡组Fig和Hct升高更显著,恢复期痊愈组与缓解组Hct、Fig两项指标差异有统计学意义,而痊愈组和健康对照组相比各指标差异均无统计学意义。结论 Fig和Hct升高、CBF降低及血小板聚集性增强可能是引起脑梗死病理性损伤的重要因素,并可作为评价脑梗死预后的客观指标。
Objective To investigate the influence of cerebral blood flow （CBF）, fibrinogen （Fig）, hematocrit （Hct）, platelets and other blood indices and electrophoresis time on the prognosis of cerebral infarction. Methods According to clinical outcome, 90 patients with acute cerebral infarction were divided into cure group, mitigation group and death group, horizontal comparison of patients in the acute phase and recovery phase Fig, Hct, platelet electrophoresis time,and calculate the CBF and compared wth the control group. Results Patients with acute cerebral infarction acute phase CBF decreased in each group,Fig were abnormal,platelet electrophoresis time increases,Fig, Hct to ease the group and death group increased significantly,the two indicators associated with the progression of the disease significantly;CBFand Fig, Hct showed a negative correlation, platelet electrophoresis time was shown a positive correlation with Fig. Recovery group and remission Hct,Fig significantly different the two indicators, while the recovery of each group and the control group. There was no significant difference, but still had a longer electrophoresis time of platelets, suggesting that continue to enhance platelet aggregation. Conclusion Fig, Hct increased,CBF reduction and enhanced platelet aggregation may be caused by cerebral infarction an important factor in pathological damage;CBF dynamic observation and platelet electrophoresis time can be used as objective indicators of prognosis in cerebral infarction;platelet electrophoresis time of acute cerebral infarctionlater than the recovery of clinical symptoms often ease.
出处
《重庆医学》
CAS
CSCD
北大核心
2011年第24期2429-2430,共2页
Chongqing medicine
