摘要
甲基汞主要造成中枢神经系统损伤,其机制尚未被完全阐明,氧化损伤可能是甲基汞所致神经毒性的重要病因。抗氧化剂是一类低毒高效,具有多种生物活性的物质,本文就甲基汞所致脑氧化损伤的机制及几种抗氧化剂的抗氧化机制进行简要介绍,为甲基汞中毒的防治提供理论参考。
Brain is the main target organ poisoned by methylmercury,the mechanism of the neurotoxicity is still not quite clear.It was suggested that oxidative damage might play a key role in methylmercury induced neurotoxicity.Antioxidants are a kind of the substances with low toxicity and high bioactivity.In this paper,the mechanisms of neurotoxicity casued by methylmercury and the antagonistic effect of antioxidants were reviewed.
出处
《中国工业医学杂志》
CAS
北大核心
2011年第4期276-279,共4页
Chinese Journal of Industrial Medicine