摘要
目的探讨卢戈碘液染色对提高早期食道癌诊断率的临床应用。方法将普通内镜下怀疑早期食道癌的214例患者按随机数字表法分为2组,每组107例。碘染色组采用2%卢戈碘液约10mL均匀喷洒于病灶及周围黏膜,在染色异常的黏膜部位定位进行4～6点活检送病理检查;对照组常规内镜检查后对可疑病灶加以活检送病理检查。结果碘染色组诊断为早期食管癌患者15例,诊断率为14.0%(15/107),对照组诊断为早期食管癌患者3例,诊断率为2.8%(3/107)。2组诊断率比较差异有统计学意义(P<0.01)。结论卢戈碘液染色能使黏膜结构更加清晰、更加立体化、更加明确,对病变定位和目的性活检有很大的帮助,能大大提高活检的阳性率,且操作简便、安全,在基层医院有较高的应用价值。
Objective To study the clinical application of Lugol＇s iodine staining for improving the diagnostic rate of early esophageal carcinoma.Methods Two hundred and fourteen patients with suspected early esophageal carcinoma who underwent routine gastroscopy were randomly divided into two groups,with 107 patients in each group.In iodine staining group,10 mL of 2% Lugol＇s iodine was sprayed evenly onto lesions and surrounding mucosa,and biopsies were obtained from 4-6 points in abnormally stained mucosal sites.In control group,general endoscopic biopsies of suspicious lesions were sent for pathological examination.Results The diagnosis rate in iodine staining group（14.0%,15/107） was significantly higher than that in control group（2.8%,3/107）（P0.01）.Conclusion Lugol＇s iodine staining makes the mucosa structure clearer and more stereoscopic and specific,and is simple,safe and helpful for intentional biopsies and lesion location.In addition,it can improve the positive biopsy rate and had a higher value in primary hospitals.
出处
《实用临床医学（江西）》
CAS
2011年第7期17-18,28,共3页
Practical Clinical Medicine
关键词
卢戈碘液染色
早期食道癌
诊断
Lugol＇s iodine staining
early esophageal carcinoma
diagnosis
