摘要
目的探讨内镜下碘染色对早期食管癌及癌前病变的诊断价值。方法将内镜下有可疑食管病变的220例患者随机分为染色组和对照组各110例。用Lugol液对染色组进行食管黏膜染色检查,并对不染色和浅染色区进行病理活检。对照组不行Lugol液染色,仅根据临床经验进行病理活检。结果染色组不着色或浅着色69例(62.7%),活检发现食管癌14例(12.7%),其中早期食管癌3例,鳞状上皮异型增生9例(8.1%);对照组110例活检发现食管癌2例(1.8%),轻中度异型增生4例(3.6%)。两组食管癌诊断率的差异有统计学意义。结论内镜下碘染色能减少食管黏膜活检误差,提高食管癌诊断率,有助于发现早期食管癌及其癌前病变。
Objective To investigate the diagnostic value of odine staining for early endoscopic detection of esophageal cancer. Methods Two hundred and twenty patients with suspected esophageal malignancy under endoscopy were randomly divided into staining group and control group. Each group had 110 cases. Lugol＇s iodine was sprayed on esophageal mucosa under endoscopy, and biopsy of unstained or tinged area by iodine was performed in the staining group. Biopsy was performed depending on the doctor＇ s clinical experience in control group in which staining was not performed. Results Sixty-nine cases （62.7%） were unstained or tinged in staining group in which 14 cases （12.71%） were pathologically confirmed as esophageal cancers （including 3 cases of early cancer）, 9 cases of squamous cell dysplasia （including 4 middle- severe dysplasia）. Pathological examinations in control group discovered 2 cases （1.8%） of esophageal cancer and 4 cases （3.6%） of mild - moderate dysplasia. Significant difference of the diagnostic rate of esophageal cancer was observed between the two groups. Conclusion Iodine staining under endoscopy could decrease the bias of esophageal mucosa biopsy, increase the diagnostic rate of esophageal cancer, and help to detect early esophageal cancer.
出处
《现代消化及介入诊疗》
2009年第3期159-161,共3页
Modern Interventional Diagnosis and Treatment in Gastroenterology
关键词
食管肿瘤
异型增生
碘染色
内窥镜检查
Esophageal neoplasms
Dysplasia
Iodine staining
Endoscopy
