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经蝶显微手术治疗泌乳素腺瘤301例 被引量:1

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摘要 目的探讨经蝶显微手术治疗泌乳素腺瘤的临床疗效。方法分析2000年1月至2009年12月经蝶显微手术治疗301例泌乳素腺瘤的随访结果。手术采用经唇下或单鼻孔蝶窦入路,显微镜下切除肿瘤,瘤床填塞凝胶海绵或肌肉浆。结果术后3d内复查MR,鞍内生长微腺瘤、鞍外生长微腺瘤、鞍内生长大腺瘤、鞍外生长大腺瘤及巨大腺瘤的全切除率分别为97.7%(43/44例)、50.0%(1/2例)、94.4%(67/71例)、64.4%(96/149例)及22.9%(8/35例);随访1年,高泌乳素血症的缓解率分别为81.8%(36/44例)、0%(0/2例)、66.2%(47/71例)、3.4%(5/149例)及0%(0/35例)。高泌乳素血症缓解率与肿瘤全切除、生长方式及大小有关。术后并发脑脊液漏11例、短暂性尿崩9例、垂体功能低下25例、嗅觉丧失3例。结论经蝶显微手术能安全有效的切除泌乳素腺瘤及缓解高泌乳素血症.可作为局限于鞍内泌乳素微腺瘤、大腺瘤的首选治疗。
出处 《中华显微外科杂志》 CSCD 北大核心 2011年第4期335-336,共2页 Chinese Journal of Microsurgery
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  • 1Mann WA. Treatment for prolactinomas and hyperprolacti- naemia: a lifetime approach. Eur J Clin Invest, 2010, 41 : 334 - 342.
  • 2Gillam MP,Molitch ME,Lombardi G,et al. Advances in the treatment of prolactinoma. Endocr Rev, 2006,27:485 - 534.
  • 3Casanueva FF, Molitch ME, Schlechte JA, et al. Guide- lines of the pituitary society for the diagnosis and manage- ment of prolactinomas. Clin Endocrinol, 2006,65 : 265 - 273.
  • 4Kreutzer J, Buslei R, Wallaschofski H, et al. Operative treatment of prolactinomas: indications and results in a current consecutive series of 212 patients. Eur J En- docrinol, 2008,158 : 11 - 18.
  • 5Losa M, Mortini P, Barzaghi R, et al. Surgical treatment of prolactin-secreting pituitary adenomas: early results and long-term outcome. J Clin Endocrinol Metab, 2002,87: 3180 - 3186.
  • 6Santoro A, Minniti G, Ruggeri A, et al. Biochemical re- mission and recurrence rate of secreting pituitary adeno- mas after transsphenoidal adenomectomy: long-term en- docrinologic follow-up results. Surg Neurol, 2007,68 : 513 - 518.
  • 7Klibanski A. Prolactinomas. N Engl J Med, 2010,362: 1219- 1226.
  • 8王海军,何东升,岑庆君,徐伟光,蓝海,蔡友锦.侵袭海绵窦的垂体腺瘤的临床特点及经蝶显微手术治疗[J].中华显微外科杂志,2006,29(2):100-102. 被引量:6
  • 9牛朝诗,丁宛海,计颖,凌士营,姜晓峰,钱若兵,魏祥品,傅先明.经单鼻孔-蝶窦入路垂体腺瘤显微手术治疗及其策略[J].中华显微外科杂志,2008,31(2):112-115. 被引量:3

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  • 1王任直,任祖渊,苏长保,杨义,陶蔚,马文斌,尹剑.采用扩大经蝶窦入路方法切除鞍区和斜坡巨大肿瘤[J].中华医学杂志,2004,84(20):1693-1697. 被引量:21
  • 2毛志钢,王海军,何东升,陈明振,杨超,蓝海.经蝶显微手术治疗哑铃形垂体腺瘤(附33例报告)[J].中国神经精神疾病杂志,2005,31(5):376-378. 被引量:4
  • 3Ezzat S, Asa SL, Couldwell WT, et al. The prevalence of pituitary adenomas : a systematic review. Cancer, 2004, 101 : 61361 - 61369.
  • 4Vemooij MW, Ikram MA, Tanghe HL, et al. Incidental findings on brain MRI in the general population. N Engl J Med, 2007, 357:1821 - 1828.
  • 5Wilson CB. A decade of pituitary microsurgery. J Neuro- surgery, 1984,61:814 - 833.
  • 6Shou XF, Li SQ, Wang YF, et al. Treatment of pituitary adenomas with a transsphenoidal approach. Neurosurgery, 2005,56 : 249 - 256.
  • 7Mortini P, Losa M, Barzaghi R, et al. Results of transsphe- noidal surgery in a large series of patients with pituitary adenoma. Neurosurgery, 2005,56 : 1222 - 1233.
  • 8Couldwell WT, Weiss MH, Rabb C, et al. Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in 105 cases. Neuro- surgery, 2004,55 : 539 - 550.
  • 9Wu JS, Shou XF, Yao C J, et al. Transsphenoidal pituitary macroadenomas resection guided by polestar n20 low-field intraoperative magnetic resonance imaging: comparison with early postoperative high-field magnetic resonance imaging. Neurosurgery, 2009,65 : 63 - 71.
  • 10Pettersen JR, Johnsen JB, Hol PK, et al. Intraoperative MRI facilitates tumour resection during transsphenoidal surgery for pituitary adenomas. Acta Neurochir, 2011, 153 : 1367 - 1373.

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