摘要
目的总结采用经单鼻孔-蝶窦入路显微手术治疗垂体腺瘤的临床疗效。方法从2003年1月至2007年12月，经单鼻孔-蝶窦入路显微手术治疗垂体腺瘤241例．并对其临床表现、肿瘤病理、肿瘤切除率、术后并发症进行总结分析。结果垂体腺瘤241例中，全切除171例（71％）．次全切除28例（11．6％），大部分切除26例（10．7％），部分切除16例（6．6％）。术后多饮、多尿38例（15，8％）、术后视力一过性下降12例（4．9％）、术后脑脊液漏4例（1．6％）、一侧动眼神经损伤2例（0．8％），无死亡病例。除动眼神经损伤的2例外，其余病例的术后并发症在出院时已治愈。随访1—36个月，所有病例的临床症状均有不同程度改善。结论经单鼻孔-蝶窦入路显微切除垂体腺瘤手术时间缩短，创伤小，手术效果好。
Objective To analysis the therapeutic effect of microsurgery through single-nostril transsphenoidal approach on pituitary adenomas and to study the surgical skill and postoperative complications about mierosurgery for pituitary adenomas. Methods The clinical manifestations, pathological type, removal percentage, postoperative complications and followup data of 241 cases with pituitary ademoma by microsurgery through single-nostril transsphenoidal approach were analysed retrospectively. Results 171 （71%） cases were achieved total tumor removal, 28 （11.6% ） cases were achieved subtotal tumor removal, 26（10.7%） cases were achieved most tumor removal and 16（6.6%） cases were achieved partial tumor removal. Most of patients achieved better results, however there were 38（15.8%） cases with diabetes insipidus, 12（4.9%） cases with transient worse sight, 4（1.6%） cases with cerebrospinal fluid leakage, 2 （0.8%） cases with oculomotor paralysis, and no death. The postoperative complications were cured and outcome was considered as good. The follow-up period was 1-36 months in 241 patients and the clinical symptoms were improved by different degrees. Conclusion Pituitary adenomas can be treated by microsurgery through single-nostril transsphenoidal approach due to the time of operation shorten, the postoperative complications.
出处
《中华显微外科杂志》
CSCD
北大核心
2008年第2期112-115,共4页
Chinese Journal of Microsurgery
基金
安徽省临床医学重点学科建设专项基金项目（2004年）
关键词
垂体腺瘤
单鼻孔-蝶窦入路
显微手术
Pituitary adenoma
Single-nostril transsphenoidal approach
Microsurgical operation
