摘要
目的探讨恶性肿瘤生存者癌痛治疗与生存质量的关系。方法对入选患者给予三阶梯止痛治疗,应用数字评分疼痛分级法及EORTC QLQ-C30问卷调查表分别对止痛治疗前后患者进行疼痛测定及生活质量测定,对结果进行比较分析。结果 (1)使用三阶梯止痛治疗后,中度疼痛缓解率为95.3%,重度疼痛缓解率为85.3%,疼痛总缓解率为88.4%;不良反应主要表现为恶心、呕吐、便秘等。(2)按照三阶梯止痛疗法疼痛治疗后患者生活质量较好,中、重度癌痛患者社会功能、情绪功能、躯体功能、失眠、整体质量均明显改善(P<0.01);中度疼痛患者生活质量得分为65.49±8.54,重度疼痛患者生活质量得分33.38±10.67,与治疗前比较差异均有统计学意义(P<0.01)。结论三阶梯止痛疗法能明显缓解癌性疼痛,有效地提高恶性肿瘤生存者的生活质量。
Objective To evaluate the pain relief therapy for improving quality of life in cancer patients. Methods The quality of life and pain levels were assessed by EORTC QLQ-C30 questionnaire and pain grading method. Results After treatment of three-step analgesic ladder the overall response rate of pain was 88.4%,that in moderate pain was 95.3% and in severe pain was 85.3%.Adverse reactions included nausea,vomiting and constipation.After treatment,the social functioning,emotional functioning,physical functioning,insomnia and global health status in cancer patients were significantly improved（P0.01）.The global health score in patients with moderate pain was 65.49±8.54,in severe pain patients was 33.38±10.67,which were statistically significant compared to that before treatment（P0.01）. Conclusion Three-step analgesic therapy can relieve cancer pain and effectively improve the quality of life for cancer patients.
出处
《实用肿瘤杂志》
CAS
北大核心
2011年第4期414-417,共4页
Journal of Practical Oncology
基金
2007年首都医学发展基金资助联合攻关项目(2007-1049)
关键词
肿瘤
生活质量
疼痛
neoplasms
quality of life
pain
