摘要
对４３４例冠心病患者以规范的流行病学调查方法对常见危险因素进行了调查和测量，分成中青年组、老年前期组和老年组三个年龄层比较早发和晚发冠心病的危险因素的异同。单因素分析显示：早发冠心病的主要危险因素是男性、吸烟史、冠心病、高血压和脑卒中家族史，其优势比（ＯＲ）分别为３．４５、２．５８、２．１４、２．０７和２．０８，早发冠心病组每日吸烟量显著高于其他两组（Ｐ＜０．０５）。多因素分析结果显示：被筛选进入Ｌｏｇｉｓｔｉｃ回归方程的变量是高血压病史、高血压和冠心病家族史、每日吸烟量、血清总胆固醇和高密度脂蛋白水平。
An
epidemiological investigation on major risk factors of coronary heart disease(CHD) was
conducted in 434 CHD patients.Participants were divided into three groups(young and middle
age,preelderly and elderly)according to age.Univariable analysis indicated that odds ratio(OR)
of family history of CHD was 2.97(95% CI,1.395.82) when compared with preelderly group.With
respect to elderly group,odds ratios of male,cigarette smoking,family history of
CHD,hypertension and stroke were 3.45(95%CI,1.47￣8.35),2.58(95% CI,1.38￣4.86),2.14(95%CI,
1.10￣4.15),2.07(95% CI,1.18￣3.69) and 2.08(95% CI,0.99￣4.7) respectively.Means of
cigarette smoking perday in youngest group was significantly higher than that of two elder
groups.Multiple variables analysis indicated that variables being selected into Logistic
equation in former analysis were physical exercise,family history of CHD and number of
cigarettes perday and in latter analysis were history of hypertension,family history of CHD and
hypertension,means of cigarette perday and level of serum high density lipoprotein(HDLC) and
total cholesterol(TC).In conclusion,male,cigarette smoking,family history of CHD,hypertension
and stroke,elevated TC level and decreased HDLC level may contribute to development of
premature CHD.
出处
《中国慢性病预防与控制》
CAS
1999年第3期102-104,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
关键词
冠心病
危险因素
年龄
Coronary heart disease\ Risk factors\ Age smoking
