摘要
目的探讨知柏地黄汤加减治疗高血压合并慢性尿路感染的临床疗效特点。方法选择2010年3月-2011年2月,收治的高血压合并慢性尿路感染患者32例,随机分成试验组和对照组,所有患者在给予常规降压治疗的同时,均依据药敏试验给予相应的抗菌药物进行抗炎治疗,试验组患者在此基础上,加用知柏地黄汤加减进行辅助治疗,对2组患者慢性尿路感染的临床疗效及患者血压的变化进行比较分析。结果与对照组相比,试验组患者慢性尿路感染的痊愈率和总有效率均明显提高,分别达到43.75%和93.75%,无效率明显降低,仅为6.25%,差异均有统计学意义(P<0.05);与治疗前相比,2组患者治疗后收缩压和舒张压均有所降低,另外,与对照组相比,试验组患者治疗后收缩压和舒张也有所降低,但差异无统计学意义。结论知柏地黄汤加减,对治疗高血压合并慢性尿路感染有明显的疗效、对患者的血压有一定的改善,在临床上有推广应用价值。
OBJECTIVE To probe into the clinical effect of Zhibai Dihuang decoction for treatment of hypertension associated with chronic urinary tract infection. METHODS The patients with hypertension and 32 patients with chronic urinary tract infections selected from Mar 2010 to Feb 2011 were randomly divided into experimental and control groups, all the patients were treated with conventional antihypertensive therapy at the same time, and were given to the appropriate antibiotics for anti-inflammatory treatment based on sensitivity Antibiotic. Experimental group on this basis, plus Zhibai Decoction treated with adjuvant therapy in patients with chronic urinary tract infection in two groups of clinical efficacy and changes in blood pressure were compared. RESULTS Compared with control group, the experimental group of patients with chronic urinary tract infection cure rate and total effective rate were increased, arriving at 43.75% and 93.75% respectively, only 6.25% for the decrease of the effective rate, there were significant differences （P〈0.05）. At the same time, compared with control group, the experimental group, systolic and diastolic after treatment were also reduced, there were also significant differences （P〈0.05）. CONCLUSION Zhibai DiHuang Decoction for the treatment of hypertension in patients with chronic urinary tract infection has significant efficacy and can improve the hypertension in a certain degree, which is worthy of the clinical promotion.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第14期2946-2948,共3页
Chinese Journal of Nosocomiology
关键词
知柏地黄汤
高血压
慢性尿路感染
疗效
Zhibai Dihuang decoction
Hypertension
Chronic urinary tract infection
Efficacy
