摘要
目的了解妊娠妇女的体质量、血清瘦素、脂联素与胰岛素抵抗之间的关联度。方法通过检测孕妇妊娠早期、中期、晚期血清脂联素(APN),瘦素(LP)、空腹血糖(FINS),同时测量身高,体质量,计算体质指数(BMI)、孕期体质量增加值和胰岛素抵抗指数(HOMA-IR),来探讨孕前体质量、孕期体质量增长与孕妇糖代谢间的关系。结果胰岛素抵抗与孕周无显著性相关,与孕期BMI、血清瘦素以及脂联素水平呈正相关。结论糖尿病对母婴的危害较大,对孕妇的管理和围产期监护,饮食控制治疗尤为重要,要注意补充脂联素充沛的食物,减少可能导致肥胖的食物摄入,才能有效的降低糖尿病的发生率。
Objective To investigate the relationship of insulin resistance to body weight, and serum leptin and adiponectin levels in pregnant women. Methods Serum adiponectin （APN）, leptin （LP）, fasting blood glucose （FBG）, body height and weight were measured, and body mass index （BMI）, gestational weight gain and insulin resistance index （HOMA -IR） were calculated in early, middle and late pregnancy in pregnant women. The relationship of body weight before pregnancy, gestational weight gain and sugar metabolism were analyzed. Results Insulin resistance and gestational age was no significant correlation, pregnancy BMI, serum lepfin and adiponectin levels were positively related to insulin resistance. Conclusion Harmful to the mother＇s diabetes, the management of pregnant women and perinatal care, diet therapy is particularly important to pay attention to add adiponectin plenty of food, reducing food intake may lead to obesity, diabetes may effectively reduce the incidence of diabetes in pregnant women.
出处
《临床和实验医学杂志》
2011年第14期1077-1078,共2页
Journal of Clinical and Experimental Medicine
关键词
妊娠
糖耐量异常
体质量
瘦素
脂联素
胰岛素抵抗
Pregnancy
Abnormal glucose tolerance
Weight
Leptin
Adiponectin
Insulin resistance
