摘要
目的探讨眼镜蛇毒对大鼠脑桥网状核c-fos阳性神经元表达的影响。方法采用免疫组织化学方法,观察并比较c-fos阳性神经元在眼镜蛇毒组、生理盐水组、正常对照组大鼠脑桥网状核的表达。结果眼镜蛇毒组大鼠脑桥网状核c-fos阳性神经元比生理盐水组、正常对照组表达明显增强(P<0.05)。结论眼镜蛇毒对大鼠脑桥网状核c-fos表达有上调作用。
Objective To investigate the effects of Naja naja atra venom on the expression of c-fos in pons reticular nucleus of rats. Methods The methods of immunohistochemistry technique were used to observe the different expression of c-fos positive cells in Naja naja atra venom group,saline group and control group. Results The number of c-fos positive cells in pons reticular nucleus of Naja naja atra venom group were higher markedly than that of saline and control groups（P〈0.05）. Conclusion Naja naja atra venom could increase the expression of c-los in pons reticular nucleus of rats.
出处
《蛇志》
2011年第2期93-95,131,共4页
Journal of Snake
基金
安徽省教育厅科研基金课题(项目编号:KJ2009B291Z)
